DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment NimC2 and Ccbe1

DIOPT Version :9

Sequence 1:	NP_001285922.1	Gene:	NimC2 / 34818	FlyBaseID:	FBgn0028939	Length:	701	Species:	Drosophila melanogaster
Sequence 2:	NP_848908.1	Gene:	Ccbe1 / 320924	MGIID:	2445053	Length:	408	Species:	Mus musculus

Alignment Length:	279	Identity:	63/279 - (22%)
Similarity:	93/279 - (33%)	Gaps:	111/279 - (39%)

- Green bases have known domain annotations that are detailed below.

  Fly    79 PLCNDCGAS----GKCLLPNVCLCGKGYV-SRKDHGHCEPE------CSES--------CV--NG 122
            ||.:..||:    ||.|.|.:.|...|:. :.::    |||      |||:        |:  :|
Mouse     5 PLPSRGGAAKRQLGKSLGPLLLLLALGHTWTYRE----EPEDRDREVCSENKITTTKYPCLKSSG 65

  Fly   123 KCVAPDECECLAGHRFVNG----------SQTACEPICVEDCANGRCLETGKCLCNNGYQ--RDE 175
            :.......:|..|::||.|          :|..||..|.::.  ||.|    |.|..||:  |:.
Mouse    66 ELTTCFRKKCCKGYKFVLGQCIPEDYDICAQAPCEQQCTDNF--GRVL----CTCYPGYRYDRER 124

  Fly   176 KLKKCVPICQDACYHGDCVAPNECRCHPGHEQRLGVPWICDPICSSGCANGYCQGAEVCACKMGY 240
            ..|:..|.|.|.   .:|...|...|                             |.:|.
Mouse   125 HQKRERPYCLDI---DECATSNTTLC-----------------------------AHICI----- 152

  Fly   241 AHKDNTLASGCEPVCNPPCTNGTCISPGHCACSEGHVFAEGSRHECVPSCRSGCENGYCSSPGRC 305
                ||:.|                  .||.|.||::..:..|     :|..|  :.|.:..|..
Mouse   153 ----NTMGS------------------YHCECREGYILEDDGR-----TCTRG--DKYPNDTGHE 188

  Fly   306 ECHEGFEKTSPHRCSPTCR 324
            |..|...|..  .|..||:
Mouse   189 EKSENEVKAG--TCCATCK 205

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
NimC2	NP_001285922.1	None
Ccbe1	NP_848908.1	EGF_CA	135..176	CDD:214542	15/104 (14%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	246..335
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	361..408
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1218
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900