Protein Alignment NimC2 and Stab2

DIOPT Version :10

• Sequence 1: NP_788047.1
• Gene: NimC2 / 34818
• FlyBaseID: FBgn0028939
• Length: 701
• Species: Drosophila melanogaster
• Sequence 2: XP_038934443.1
• Gene: Stab2 / 282580
• RGDID: 628822
• Length: 2561
• Species: Rattus norvegicus
• Alignment Length: 936
• Identity: 198/936 - (21%)
• Similarity: 258/936 - (27%)
• Gaps: 440/936 - (47%)

  Fly    40 ANCTTNCGPLVGRTRTETYLGFTDVCCDGYIRDENNECVP----LCNDCGASGKC---LLPN-VC 96
            :.|...|...|...|          ||.|:.   ..:|.|    ....|..:|:|   |..| .|
  Rat   716 SGCARYCNVTVEIPR----------CCKGFF---GPDCTPCPGGFLTPCSGNGQCMDGLAGNGTC 767

  Fly    97 LCGKGYVSR-----KDHGHCEPECSES--CVNGKC--VAPDECECLAG-------HRFVNGSQTA 145
            :|..|:...     .|.....|.|:.:  ||:|.|  ....:..||:|       .||.:...:|
  Rat   768 ICQDGFQGSMCQFCSDPNRYGPRCNRTCLCVHGTCDNRLDSDGACLSGTCREGTAGRFCDKQTSA 832

  Fly   146 CEPICVEDC-ANGRC---LETGKCLCNNGYQRDEKL--KK-----------CVP----------- 182
            |.|. |:.| .:..|   .:|..|:||.||:.|..|  ||           |.|
  Rat   833 CGPY-VQFCHIHASCEYSNKTASCVCNEGYEGDGVLCSKKDPCLGLTSRGGCSPNAECIQTSTGT 896

  Fly   183 ---ICQDACYHG---DCVAPNECRCHPGHEQRLGVPWICDPICSSGC-ANGYC----QGAEVCAC 236
               :||.. :.|   |||..|.|.          :|      .|.|| .|..|    .|...|.|
  Rat   897 YSCVCQQG-WTGNGRDCVGINNCL----------LP------SSGGCHDNATCLYVGPGQNECEC 944

  Fly   237 KMGYAHKDNTLASGCEPV---------CNPPCT-NGTCISPGHCACSEGH--------------- 276
            |.|:  :.|.:  .|||:         |:|..| ..|......|.|.||:
  Rat   945 KKGF--RGNGI--DCEPIISCLEQTEKCHPLATCQSTSSGVWSCVCREGYEGNGVLCYGNVLMEL 1005

  Fly   277 -------VFAEGSRHECVPSCRSGCENGYCSSPGRCECHEGFEK--------------------- 313
                   ||.:...:..:.|..|...|.....|.|    ..||.
  Rat  1006 SFLPEAAVFYQWINNASLQSVLSTTSNLTVLVPSR----RAFEDMDQNEKSFWLSRNNIPALIKY 1066

  Fly   314 ---------------TSPHRCSPTCRPGC-------------------GQNSRC----------- 333
                           :|||..:.:.:...                   |.|:..
  Rat  1067 HILLGKYGVADLQALSSPHMLATSLQGNFLQLDKADGNITIEGASIVDGDNAATNGVVHIINKVL 1131

  Fly   334 --------AAPDTC--------------------------ACDVGYVFV---------------- 348
                    :.|...                          |.|...|||
  Rat  1132 VPQRGLTGSLPSLLTRLEQMPGYSIFRGYIIHYNLASAIEAADAYTVFVPNNEAIENYIREKKAT 1196

  Fly   349 -----------------------NGSTTECE-------PFCPRN--------------------- 362
                                   ||...|..       .|..||
  Rat  1197 SLKEDILRYHVVLGEKLLKNDLHNGMHRETMLGFSYLLAFFLRNDQLYVNEAPINYTNVATDKGV 1261

  Fly   363 --------------CRN----------GICSSPGVC-----TCLEGFQALLSFY----------C 388
                          |.|          |.||....|     ...|..:.:.|.|          |
  Rat  1262 IHGLEKVLEIQKNRCDNNDTIIVRGECGKCSQQAPCPLETKPLRETRKCIYSIYFMGKRSVFIGC 1326

  Fly   389 IPVCSKTCIHGSCVAPNECRCFTGYRPN----PSLGANVCEPICSQGCVHGFCI----APEICQC 445
            .|.|.:|.|..:|     |..|.|  |.    |..|.|||..       :|||:    ....|||
  Rat  1327 QPQCVRTIITRAC-----CAGFFG--PQCQACPGRGQNVCSG-------NGFCLDGVNGTGTCQC 1377

  Fly   446 DLGFIKRWATGT-CEP--------HCPQ--KCVNSHC----LGSGVCRC---YEGYKLRPGSTSI 492
            .|||     :|| ||.        ||.|  .||:..|    ||.|.|.|   :.|.|
  Rat  1378 GLGF-----SGTACETCTEGKYGIHCDQACSCVHGRCSQGPLGDGSCDCDVGWRGVK-------- 1429

  Fly   493 CDPECQPGCRNGTC-------VEPN---SCACFAGYEDTKVPYECVPSCRPRCENGRCS------ 541
            ||.|......||||       ::|:   ||.|.||:.........:.:|  ...||.||
  Rat  1430 CDMEITTDNCNGTCHTSANCLLDPDGKASCKCAAGFRGNGTVCTAINAC--ETSNGGCSTKADCK 1492

  Fly   542 --SPGH--CECDPGHVVTNSS----EPNSCRPQ---CQEQCINAEC--VAPEK--CACLPRYRFL 591
              :||:  |.|..|:  |...    |.|.|...   |..   ||||  ..|.:  |.|||:|
  Rat  1493 RTTPGNRVCVCKAGY--TGDGIVCLEINPCLENHGGCDR---NAECTQTGPNQAVCNCLPKY--- 1549

  Fly   592 PDSSTECEPICS--KGCLSGQECVAP 615
                |....:||  ..||:.....:|
  Rat  1550 ----TGDGKVCSLINVCLTNNGGCSP 1571

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
NimC2	NP_788047.1	None
Stab2	XP_038934443.1	EGF_3	254..283	CDD:463759
		EGF_3	334..369	CDD:463759
		Fasciclin	390..512	CDD:396845
		FAS1	511..658	CDD:441906
		EGF_3	840..868	CDD:463759	9/27 (33%)
		EGF_3	881..912	CDD:463759	5/31 (16%)
		EGF_3	923..955	CDD:463759	11/35 (31%)
		EGF_3	961..997	CDD:463759	8/35 (23%)
		Fasciclin	1014..1133	CDD:396845	13/122 (11%)
		Fasciclin	1152..1269	CDD:396845	11/116 (9%)
		EGF_3	1478..1514	CDD:463759	11/39 (28%)
		EGF_3	1520..1556	CDD:463759	13/45 (29%)
		EGF_3	1562..1598	CDD:463759	3/10 (30%)
		Fasciclin	1629..1729	CDD:396845
		Fasciclin	1754..1885	CDD:396845
		EGF_3	2059..2084	CDD:463759
		EGF_3	2090..2125	CDD:463759
		EGF_3	2131..2168	CDD:463759
		Link_Domain	2202..2294	CDD:470631
		FAS1	2360..2449	CDD:214719