DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp28a5 and CYP705A12

DIOPT Version :9

Sequence 1:	NP_609694.1	Gene:	Cyp28a5 / 34817	FlyBaseID:	FBgn0028940	Length:	505	Species:	Drosophila melanogaster
Sequence 2:	NP_199072.1	Gene:	CYP705A12 / 834265	AraportID:	AT5G42580	Length:	499	Species:	Arabidopsis thaliana

Alignment Length:	506	Identity:	114/506 - (22%)
Similarity:	220/506 - (43%)	Gaps:	76/506 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MVLITLTLVSLVVGL-LYAVLVWNYDYWRKRGV---PGPKPKLLCGNYPNMFTMK-RHAIYDLDD 60
            ::::....:|:.:.| |::.|.:...:.:.:|.   |.|....:.|:..::.:.. .|      .
plant     4 LIIVDFQNISIFILLCLFSFLCYALFFKKPKGFDLPPSPPSLPIIGHLHHLLSSSLPH------K 62

  Fly    61 IYRQYKNKYDA---VGIFGSRSPQLLVINPALARRVFVSNFKNFHDNEIAKNIDEKTDFIFANNP 122
            .:::...||..   :.||  ..|.:||.:.::|..||.:|..|.....:..|   |...:|.::.
plant    63 SFQKLSFKYGPLLHLRIF--NFPMVLVSSASMAYEVFRTNDVNVSYRFVPVN---KDSLVFGSSG 122

  Fly   123 FSLT--GEKWKTRRADVTPGLTMGRIKTVYPVTNKVCQKLTEW-VEKQLRLGSKDGIDAKHMSLC 184
            |...  |:.||..:..::..|.  |...:........::|..: ::.|.:...|:.::...::|.
plant   123 FVTAPYGDYWKFMKKLISTKLL--RPHALELSKGNRAEELRRFCLDLQGKARKKESVEIGKVALK 185

  Fly   185 FTTEMVTDCVLGLGAESFSDKPTPIMSKINDLFNQPWTFVLFFILTSSFPSLSHLIKLRFVPVDV 249
            .|..::  |.:.:| .|.|:| ..:..:..:|.|:               |.:..:||.|    .
plant   186 LTNNII--CRMSMG-RSCSEK-NGVAERARELVNK---------------SFALSVKLFF----S 227

  Fly   250 ERFFVDLMGSAVE---------TRRAQLAAGKQFERSDFLDYILQLGEKRN------LDNRQLLA 299
            ..|..|:||.:.|         ....:...|.| :| |.:|::|:  ..||      :..:|:.:
plant   228 NMFRKDIMGVSREFDEFLERILVEHEENLEGDQ-DR-DMIDHLLE--AYRNEEAEYKITRKQIKS 288

  Fly   300 YSMTFLLDGFETTATVLAHILLNLGRNKEAQNLLREEIRSHLQDGTIAFEK-LSDLPYLDACVQE 363
            ..:...|.|.:::|..:...:..:..|......||.||.|.:....:..|. |.:||||.|.|:|
plant   289 LIVEIFLGGTDSSAQTIQWTMAEILNNPGVLEKLRAEIDSVVGGKRLIQESDLPNLPYLQAVVKE 353

  Fly   364 TIRLFPPGFMSNKLCTESIEIPNKEGPNFVVEKGTTVVVPHYCFMLDEEFFPNPQSFQPERFLEP 428
            .:||.|...:..::..||.|:  ||   |.|.:.||:||..|....|.:.:.:|..|:|||||..
plant   354 GLRLHPSAPVLLRVFGESCEV--KE---FYVPEKTTLVVNLYAVNRDPDSWEDPDMFKPERFLVS 413

  Fly   429 DAA---KTFRERGV-FMGFGDGPRVCIGMRFATVQIKAAIVELISKFNVKI 475
            ..:   :..||:.| ::.||.|.|.|..::.|.:.::.||..::..|:.:|
plant   414 SISGDEEKIREQAVKYVTFGGGRRTCPAVKLAHIFMETAIGAMVQCFDWRI 464

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp28a5	NP_609694.1	p450	33..500	CDD:299894	109/470 (23%)
CYP705A12	NP_199072.1	CYP93	72..490	CDD:410748	103/432 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D467733at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010