DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Cyp28a5 and BAS1

DIOPT Version :9

Sequence 1:	NP_609694.1	Gene:	Cyp28a5 / 34817	FlyBaseID:	FBgn0028940	Length:	505	Species:	Drosophila melanogaster
Sequence 2:	NP_180239.1	Gene:	BAS1 / 817212	AraportID:	AT2G26710	Length:	520	Species:	Arabidopsis thaliana

Alignment Length:	509	Identity:	114/509 - (22%)
Similarity:	210/509 - (41%)	Gaps:	76/509 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 VLITLTLVSLVVGLLYAVLVWN----YDYWRKRGVPGPKPKLLCGNYPNMFTM-----------K 51
            ||:...::|||:....::|.|.    .:::.|:|:.||......||...:..|           .
plant    13 VLVLSVILSLVIVKGMSLLWWRPRKIEEHFSKQGIRGPPYHFFIGNVKELVGMMLKASSHPMPFS 77

  Fly    52 RHAIYDLDDIYRQYKNKYDAVGI--FGSRSPQLLVINPALARRVFVSNFKNFHDNE---IAKNID 111
            .:.:..:...|..::..|.|..:  ||. :.:|.|.:|.|.|.:| |..:.:..||   :.|.::
plant    78 HNILPRVLSFYHHWRKIYGATFLVWFGP-TFRLTVADPDLIREIF-SKSEFYEKNEAHPLVKQLE 140

  Fly   112 EKTDFIFANNPFSLTGEKWKTRRADVTPGLTMGRIKTVYPVTNKVCQKLTEWVEKQLRLGSKDG- 175
                   .:...||.||||...|..::|...|..:|.:.||   |.:.:|:.|:|.....|::|
plant   141 -------GDGLLSLKGEKWAHHRKIISPTFHMENLKLLVPV---VLKSVTDMVDKWSDKLSENGE 195

  Fly   176 --IDAKHMSLCFTTEMVTDCVLGLGAESFSDKPTPIMSKINDLFNQPWTFVLFFIL-TSSFPSLS 237
              :|........|.::::....|   .|:.|.......:...:......|...||. ...||:..
plant   196 VEVDVYEWFQILTEDVISRTAFG---SSYEDGRAVFRLQAQQMLLCAEAFQKVFIPGYRFFPTRG 257

  Fly   238 HLIKLRFVPVDVERFFVDLMGSAVETRRAQLAAG-----KQFERSDFLDYILQLGEKRNLDNRQL 297
            :| |...:..::.:..:.|    :|.||.....|     |:....|.|..::|   .:|:..:.:
plant   258 NL-KSWKLDKEIRKSLLKL----IERRRQNAIDGEGEECKEPAAKDLLGLMIQ---AKNVTVQDI 314

  Fly   298 LAYSMTFLLDGFETTATVLAHILLNLGRNKEAQNLLREEIRS-------HLQDGTIAFEKLSDLP 355
            :....:|...|.:||:.:|....:.|..:.|.|...|:|:..       ..:|..:..:.||.:
plant   315 VEECKSFFFAGKQTTSNLLTWTTILLSMHPEWQAKARDEVLRVCGSRDVPTKDHVVKLKTLSMI- 378

  Fly   356 YLDACVQETIRLFPPGFMSNKLCTESIEIPNKEGPNFVVEKGTTVVVPHYCFMLDEEFFPNP-QS 419
                 :.|::||:||...:.:.....:::     ..:.:..||.:::|......|:..:.|. ..
plant   379 -----LNESLRLYPPIVATIRRAKSDVKL-----GGYKIPCGTELLIPIIAVHHDQAIWGNDVNE 433

  Fly   420 FQPERFLE--PDAAKTFRERGVFMGFGDGPRVCIGMRFATVQIKAAIVELISKF 471
            |.|.||.:  |.|||  ...| |:.||.|.|.|||...|.:|.|..:..:|.:|
plant   434 FNPARFADGVPRAAK--HPVG-FIPFGLGVRTCIGQNLAILQAKLTLAVMIQRF 484

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp28a5	NP_609694.1	p450	33..500	CDD:299894	105/474 (22%)
BAS1	NP_180239.1	CYP734	85..509	CDD:410732	100/437 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm3438
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910