Protein Alignment Cyp28a5 and Cyp3a57

DIOPT Version :10

• Sequence 1: NP_609694.1
• Gene: Cyp28a5 / 34817
• FlyBaseID: FBgn0028940
• Length: 505
• Species: Drosophila melanogaster
• Sequence 2: NP_001093650.1
• Gene: Cyp3a57 / 622127
• MGIID: 3646373
• Length: 503
• Species: Mus musculus
• Alignment Length: 507
• Identity: 130/507 - (25%)
• Similarity: 233/507 - (45%)
• Gaps: 78/507 - (15%)

  Fly     7 TLVSLVVGLLYAVLVWNYDY--WRKRGVPGPKPKLLCGNYPNMFT-MKRHAIYDLDDIYRQYKNK 68
            |.|.||..|::..:...|.:  ::|.|:|||||..|.||..|... |.:   :| ||.|::|...
Mouse    11 TWVLLVTSLVFFYIYGTYSHGLFKKLGIPGPKPLPLFGNIINYLDGMWK---FD-DDCYKKYGKI 71

  Fly    69 YDAVGIFGSRSPQLLVINPALARRVFVSNFKNFHDNEIAKNIDEKTDFIFAN-NPFSLTG----- 127
            :   |.:....|.|.:::|.:.:.|.|....:                :|.| .||...|
Mouse    72 W---GFYEGPQPILAIMDPEIIKIVLVKECYS----------------VFTNRRPFGPVGFLKKS 117

  Fly   128 ------EKWKTRRADVTPGLTMGRIKTVYPVTNK----VCQKLTEWVEKQLRLGSKDGIDAKHMS 182
                  |:||..|..::|..|..::|.::|:..:    :.:.|....||:..:..||...|
Mouse   118 ITISEDEEWKRLRTLLSPTFTSSKLKEMFPIMRQYGDILVRNLRREEEKEEPINMKDIFGA---- 178

  Fly   183 LCFTTEMVTDCVLGLGAESFSDKPTPIMSKINDL----FNQPWTFVLFFILTSSFPSLS---HLI 240
              ::.:::|....|:..:|.::...|.:.||..:    |..|  |:|..:|   ||.|:   .::
Mouse   179 --YSMDVITGTSCGVNIDSLNNPQDPFVQKIKKILKFKFFDP--FLLSVVL---FPFLTPIYEML 236

  Fly   241 KLRFVPVDVERFFVDLMGSAVETRRAQLAAGKQFERSDFLDYILQLGEKRN------LDNRQLLA 299
            .|...|.....||...    |:..:.......|..|.|||..::.....:.      |.:.::.|
Mouse   237 NLSIFPRQSMNFFKKF----VKKMKKDRLDYNQKNRVDFLQLMMNTQNSKGQESLKALSDLEMAA 297

  Fly   300 YSMTFLLDGFETTATVLAHILLNLGRNKEAQNLLREEI-RSHLQDGTIAFEKLSDLPYLDACVQE 363
            .::.|:..|::.|:|.::.|:..|..:.:.|..|::|| |:......:.::.|.|:.|||..|.|
Mouse   298 QTLIFIFGGYDGTSTSISFIMYELATHPDVQKKLQDEIDRALPNKAPVTYDALMDMEYLDMVVNE 362

  Fly   364 TIRLFPPGFMSNKLCTESIEIPNKEGPNFVVEKGTTVVVPHYCFMLDEEFFPNPQSFQPERFLEP 428
            ::||:|.....::...:.:||     ....:.|||.|::|.|....|.|::|.|:.|.||||.:.
Mouse   363 SLRLYPVVSRIDRFSKKDVEI-----HGVFIPKGTIVMIPIYPLHRDPEYWPEPEDFCPERFSKE 422

  Fly   429 DAAKTFRERGVFMGFGDGPRVCIGMRFATVQIKAAIVELISKFNVKINDKTR 480
            :....  :..::|.||:|||.|||||||.:.:|.|:..::..|.|:..::|:
Mouse   423 NKGNI--DPYIYMPFGNGPRNCIGMRFALISVKLAVTGVLQNFTVQPCEETQ 472

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp28a5	NP_609694.1	CYP6-like	67..499	CDD:410679	107/444 (24%)
Cyp3a57	NP_001093650.1	cytochrome_P450	67..492	CDD:477761	108/447 (24%)