Protein Alignment Cyp28a5 and Cyp3a41a

DIOPT Version :10

• Sequence 1: NP_609694.1
• Gene: Cyp28a5 / 34817
• FlyBaseID: FBgn0028940
• Length: 505
• Species: Drosophila melanogaster
• Sequence 2: NP_059092.2
• Gene: Cyp3a41a / 53973
• MGIID: 1858451
• Length: 504
• Species: Mus musculus
• Alignment Length: 511
• Identity: 133/511 - (26%)
• Similarity: 240/511 - (46%)
• Gaps: 79/511 - (15%)

  Fly     3 LITLTLVSLVVGLLYAVLVWNYDYWRKRGVPGPKPKLLCGNYPNMFTMKRHAIYDLD-DIYRQYK 66
            |.|..|:::::.|||......:..::|:|:|||||....|...|.:    ..::..| :.|.:|.
Mouse     9 LDTWVLLAIILVLLYRYGTRTHGLFKKQGIPGPKPLPFLGTVLNYY----KGLWKFDMECYEKYG 69

  Fly    67 NKYDAVGIFGSRSPQLLVINPALARRVFVSNFKNFHDNE--------IAKNIDEKTDFIFANNPF 123
            ..:   |:|..:.|..::.:|.:.:.|.|....:...|.        ::|.|....|
Mouse    70 KTW---GLFDGQMPLFVITDPEMIKNVLVKECFSVFTNRREFGPVGIMSKAISISKD-------- 123

  Fly   124 SLTGEKWKTRRADVTPGLTMGRIKTVYPVTNKVCQKLTEWVEKQLRLGS----KDGIDAKHMSLC 184
                |:||..||.::|..|.|::|.::||..:....|.:::.::...|.    ||.:.|
Mouse   124 ----EEWKRYRALLSPTFTSGKLKEMFPVIEQYGDILVKYLMQEAEKGKPVTMKDVLGA------ 178

  Fly   185 FTTEMVTDCVLGLGAESFSDKPTPIMSKINDL----FNQPWTF--VLFFILTSSFPSLSHLIKLR 243
            ::.:::|....|:..:|.::...|.:.|...:    |..|..|  |||..||..:    .::.:.
Mouse   179 YSIDVITSTSFGVNVDSLNNPEDPFVEKAKGILRVDFFDPLVFSVVLFPFLTPVY----EMLNIC 239

  Fly   244 FVPVDVERFFVDLMGSAVETRRAQLAAGKQFERSDFLDYILQL-------GEKRNLDNRQLLAYS 301
            ..|.|...||...:....|:|    ...||..|.|||..::..       ...:.|.:.::.|.|
Mouse   240 MFPKDSIEFFKKFVNRMKESR----LDSKQKHRVDFLQLMMNAHNNSKDKDSHKALSDMEITAQS 300

  Fly   302 MTFLLDGFETTATVLAHILLNLGRNKEAQNLLREEIRSHLQDGTI------AFEKLSDLPYLDAC 360
            :.|:..|:|||::.|:..|..|..:.:.|..|:|||     |.|:      .::.:.::.|||..
Mouse   301 IVFIFAGYETTSSTLSFTLYCLATHPDIQKKLQEEI-----DETLPNKAPPTYDTVMEMEYLDMV 360

  Fly   361 VQETIRLFPPGFMSNKLCTESIEIPNKEGPNFV-VEKGTTVVVPHYCFMLDEEFFPNPQSFQPER 424
            :.||:||:|.|....:.|.:.:|:      |.| :.||:||::|.|....|.:.:|.|:.|||||
Mouse   361 LNETLRLYPIGNRLERFCKKDVEL------NGVYIPKGSTVMIPSYALHHDPQHWPEPEEFQPER 419

  Fly   425 FLEPDAAKTFRERGVFMGFGDGPRVCIGMRFATVQIKAAIVELISKFNVKINDKTR 480
            |.:.:  |...:..::|.||.|||.|||||||.:.:|.|:.:::..|:.:...:|:
Mouse   420 FSKEN--KGSIDPYLYMPFGIGPRNCIGMRFAFMTMKLALTKVMQNFSFQPCQETQ 473

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp28a5	NP_609694.1	CYP6-like	67..499	CDD:410679	115/446 (26%)
Cyp3a41a	NP_059092.2	CYP3A	67..493	CDD:410743	116/449 (26%)