Protein Alignment Cyp28a5 and Cyp3a73

DIOPT Version :10

• Sequence 1: NP_609694.1
• Gene: Cyp28a5 / 34817
• FlyBaseID: FBgn0028940
• Length: 505
• Species: Drosophila melanogaster
• Sequence 2: XP_038945885.1
• Gene: Cyp3a73 / 498198
• RGDID: 1595705
• Length: 504
• Species: Rattus norvegicus
• Alignment Length: 500
• Identity: 119/500 - (23%)
• Similarity: 238/500 - (47%)
• Gaps: 57/500 - (11%)

  Fly     3 LITLTLVSLVVGLLYAVLVWNYDYWRKRGVPGPKPKLLCGNYPNMFTMKRHAIYDLDDIYRQYKN 67
            |.|..|:::::.|.|......:..::|:|:|||||....|...|.:    ..::..|  ...||.
  Rat     9 LETWLLLAIILVLFYRFGTRTHGIFKKQGIPGPKPLPFLGTVLNYY----RGLWKFD--MECYKK 67

  Fly    68 KYDAVGIFGSRSPQLLVINPALARRVFVSNFKNFHDNE--------IAKNIDEKTDFIFANNPFS 124
            .....|:|..::|...:::..:.:.|.|....:...|.        ::|:|....|
  Rat    68 CGKIWGLFDGQTPVFAIMDTEMIKSVLVKECFSVFTNRRNIGPVGIMSKSISVAKD--------- 123

  Fly   125 LTGEKWKTRRADVTPGLTMGRIKTVYPVTNKVCQKLTEWVEKQLRLGSKDGIDAKHMSLCFTTEM 189
               |:||..||.::|..|.||:|.::|:.......|.:::::::..|..  :..|.:...::.::
  Rat   124 ---EEWKRYRAFLSPTFTSGRLKEMFPIIEHYGDILVKYLKQKVEKGKP--LAMKEVFGAYSMDV 183

  Fly   190 VTDCVLGLGAESFSDKPTPIMSKIN-----DLFNQPW-TFVLFFILTSSFPSLSHLIKLRFVPVD 248
            :|.....:...|.::...|.:.|:.     |.|:..: :.|||..||..:    .::.:...|.|
  Rat   184 ITSTSFEVNINSINNPKDPFVEKVKKFQRFDFFDPLFLSVVLFPFLTPIY----EMLNICLFPKD 244

  Fly   249 VERFFVDLMGSAVETRRAQLAAGKQFERSDFLDYILQLGEK-------RNLDNRQLLAYSMTFLL 306
            ...||...:....:||    ...|...|.|||..::.....       :.|.:.:::|.::.|:.
  Rat   245 SVAFFQKFVYRMKQTR----LDSKHKHRVDFLQLMMNAHNNSKDKVSHKALSDIEIVAQAIIFIF 305

  Fly   307 DGFETTATVLAHILLNLGRNKEAQNLLREEI-RSHLQDGTIAFEKLSDLPYLDACVQETIRLFPP 370
            ..:|||::.|:.:|.:|..:.::|..|:||| |:........::.:.::.|||..:.||.||:|.
  Rat   306 ASYETTSSTLSFVLYSLATHPDSQKKLQEEIDRALPNKAPPTYDTVMEMEYLDMVLNETPRLYPI 370

  Fly   371 GFMSNKLCTESIEIPNKEGPNFVVEKGTTVVVPHYCFMLDEEFFPNPQSFQPERFLEPDAAKTFR 435
            |:...::|.:.|::     ....:.||:.|::|.|....|.:.:|.|:.|.||||.:.:  |...
  Rat   371 GYRLERVCKKDIKL-----DGVFIPKGSVVMIPFYTLQHDPQHWPEPEEFLPERFSKEN--KGSI 428

  Fly   436 ERGVFMGFGDGPRVCIGMRFATVQIKAAIVELISKFNVKINDKTR 480
            :..|::.||:|||.|||||||.:.:|.|:.:::..|:.::.::|:
  Rat   429 DPYVYLPFGNGPRNCIGMRFALMNMKLALTKVLQNFSFQLCEETQ 473

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp28a5	NP_609694.1	CYP6-like	67..499	CDD:410679	102/435 (23%)
Cyp3a73	XP_038945885.1	CYP3A	67..493	CDD:410743	102/435 (23%)