Protein Alignment Cyp28a5 and cyp51

DIOPT Version :10

• Sequence 1: NP_609694.1
• Gene: Cyp28a5 / 34817
• FlyBaseID: FBgn0028940
• Length: 505
• Species: Drosophila melanogaster
• Sequence 2: NP_001001730.2
• Gene: cyp51 / 414331
• ZFINID: ZDB-GENE-040625-2
• Length: 499
• Species: Danio rerio
• Alignment Length: 520
• Identity: 110/520 - (21%)
• Similarity: 193/520 - (37%)
• Gaps: 118/520 - (22%)

  Fly     2 VLITLTLVSLVVGLLYAVLVWNYDYWRKR---GVPGPKPKLLCGNYPNMFTMKRHAIYDLDDIYR 63
            ||:|.::.:|.:|....:|...:.....:   .:|...|.|     .......|..|..|:..|.
Zfish    23 VLLTASVFTLTLGYFSKLLFTQHSSEHTKYPPHIPSSLPFL-----GQAVAFGRSPIEFLEKAYE 82

  Fly    64 QYKN--KYDAVG-----IFGSRSPQLLVINPALARRVFVSNFKNFHDNEIAKNIDEKTDFIFAN- 120
            ||..  .:..||     :.||.:..|:                 |:    :||.|...:.::|.
Zfish    83 QYGPVVSFTMVGKTFTYLLGSDAAALM-----------------FN----SKNEDLNAEDVYARL 126

  Fly   121 --------------NPFSLTGEKW-KTRRADVTPGLTMGRIKT-VYPVTNKVCQKLTEWVEKQLR 169
                          ||..|..:|. ||       ||.:.:.|. |..:..:.......|.|.
Zfish   127 TTPVFGKGVAYDVPNPLFLEQKKMLKT-------GLNIAQFKQHVEIIEEETKDYFRRWGES--- 181

  Fly   170 LGSKDGIDAKHMSLCFTTEMVTDCVLGLGAESFSDKPTPIMSKINDLF--------NQPWTFVLF 226
             |.::..||....:..|   .:.|:.|....|..|:      ::..|:        :..|....:
Zfish   182 -GERNLFDALSELIILT---ASRCLHGCEIRSLLDE------RVAQLYADLDGGFTHAAWLLPGW 236

  Fly   227 FILTSSFPSL-----SHLIKLRFVPVDVERFFVDLMGSAVETRRAQLAAGKQFERSDFLDYILQL 286
            ..|    ||.     :||        ::::.|.::    ::.||....     :..|.|..::..
Zfish   237 LPL----PSFRRRDRAHL--------EIKKIFYNV----IKKRREDTE-----KHDDILQTLIDA 280

  Fly   287 GEK--RNLDNRQLLAYSMTFLLDGFETTATVLAHILLNLGRNKEAQNLLREEIRSHLQD--GTIA 347
            ..|  |.|.:.::....:..||.|..|::|..|.:...|.|::..|.....|.:|...:  ..:.
Zfish   281 TYKDGRPLSDDEIAGMLIGLLLAGQHTSSTTSAWMGFFLARDRALQERCYSEQKSVCGEELPPLH 345

  Fly   348 FEKLSDLPYLDACVQETIRLFPPGFMSNKLCTESIEIPNKEGPNFVVEKGTTVVVPHYCFMLDEE 412
            :::|.||..||.|::||:||.||.....::.    :.|.|.| .:.:..|..|.|........::
Zfish   346 YDQLKDLSLLDRCLKETLRLRPPIMTMMRMA----KTPQKVG-EYTIPPGHQVCVSPTVNHRLQD 405

  Fly   413 FFPNPQSFQPERFLEPDAAKTFRERGVFMGFGDGPRVCIGMRFATVQIKAAIVELISKFNVKIND 477
            .:.....|.|:|:|..:.|.  .|:..::.||.|...|||..||.||||.....|:..|:.::.|
Zfish   406 TWAERLDFDPDRYLHDNPAA--GEKFAYIPFGAGRHRCIGENFAYVQIKTIWSTLLRMFDFELVD 468

  Fly   478  477
            Zfish   469  468

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp28a5	NP_609694.1	CYP6-like	67..499	CDD:410679	95/452 (21%)
cyp51	NP_001001730.2	CYP51-like	80..491	CDD:410668	98/458 (21%)