DRSC/TRiP Functional Genomics Resources

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Protein Alignment Cyp28a5 and Cyp6a8

DIOPT Version :9

Sequence 1:NP_609694.1 Gene:Cyp28a5 / 34817 FlyBaseID:FBgn0028940 Length:505 Species:Drosophila melanogaster
Sequence 2:NP_523749.2 Gene:Cyp6a8 / 36666 FlyBaseID:FBgn0013772 Length:506 Species:Drosophila melanogaster


Alignment Length:525 Identity:145/525 - (27%)
Similarity:254/525 - (48%) Gaps:48/525 - (9%)


- Green bases have known domain annotations that are detailed below.


  Fly     4 ITLTLVSLVVGLLYAVLVW----NYDYWRKRGVPGPKPKLLCGNYPNMFTMKR-HAIYDLDDIYR 63
            :|..|..:.|.|| |:|.:    ...|:::||:|...|.|:.||...:...|. |.|:  .|.|.
  Fly     3 LTYILFQVAVALL-AILTYYIHRKLTYFKRRGIPFVAPHLIRGNMEELQKTKNIHEIF--QDHYN 64

  Fly    64 QYK-NKYDAVGIFGSRSPQLLVINPALARRVFVSNFKNFHDNEIAKNIDEKTDFIFANNPFSLTG 127
            ::: :|...||.|..:||...||:..||:::.:.:|.||.:..|..|  ||.|.|.| :.|:|.|
  Fly    65 KFRESKAPFVGFFFFQSPAAFVIDLELAKQILIKDFSNFSNKGIFYN--EKDDPISA-HLFNLDG 126

  Fly   128 EKWKTRRADVTPGLTMGRIKTVYP----VTNKVCQKLTEWVEKQLRLGSKDGIDAKHMSLCFTTE 188
            .:|:..|..::...|.|::|.:||    |.|:....:.|.|.|...|..:|      :...||.:
  Fly   127 AQWRLLRNKLSSTFTSGKMKLMYPTVVSVANEFMTVMHEKVPKNSVLEIRD------LVARFTVD 185

  Fly   189 MVTDCVLGLGAESFSDKPTPIM--SKINDLFNQPWTFVLFFILTSSFPSLSHLIKLRFVPVDVER 251
            ::..|..|:...|..|:....:  .|.:.:..:..|.:..|:  .|:|.|:..:.:......::.
  Fly   186 VIGTCAFGIQCNSLRDEKAEFLYFGKRSLVDKRHGTLLNGFM--RSYPKLARKLGMVRTAPHIQE 248

  Fly   252 FFVDLMGSAVETRRAQLAAGKQFERSDFLDYILQLGEK-----------RNLDNRQLLAYSMTFL 305
            |:..::...|..|..:     ..:|:||:|.:::|..:           |.|...::||.:..|.
  Fly   249 FYSRIVTETVAVREKE-----HIKRNDFMDMLIELKNQKEMTLENGDVVRGLTMEEVLAQAFVFF 308

  Fly   306 LDGFETTATVLAHILLNLGRNKEAQNLLREEIRSHLQ--DGTIAFEKLSDLPYLDACVQETIRLF 368
            :.||||:::.:...|..|.:|.:.|:.:|.|:...::  |....:|...||.||:..:.||:||:
  Fly   309 IAGFETSSSTMGFALYELAKNPDIQDKVRAEVEEVIEQHDQNFTYECTKDLKYLNQVLDETLRLY 373

  Fly   369 PPGFMSNKLCTESIEIPNKEGPNFVVEKGTTVVVPHYCFMLDEEFFPNPQSFQPERFLEPDAAKT 433
            ......:::..:...:|..  ||||:|.|.:|::|......|...:|.|..|:||||...::|. 
  Fly   374 TIVPNLDRMAAKRYVVPGH--PNFVIEAGQSVIIPSSAIHHDPSIYPEPFEFRPERFSPEESAG- 435

  Fly   434 FRERGVFMGFGDGPRVCIGMRFATVQIKAAIVELISKFNVKINDKTRKDNDYEPGQIITGLRGGI 498
             |....::.||||||.|||:||..:|.:..:..||..|......||.....|:|...:.|::.||
  Fly   436 -RPSVAWLPFGDGPRNCIGLRFGQMQARIGLALLIRNFKFSTCSKTPNPLVYDPKSFVLGVKDGI 499

  Fly   499 WLDLE 503
            :|.:|
  Fly   500 YLKVE 504

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Cyp28a5NP_609694.1 p450 33..500 CDD:299894 133/487 (27%)
Cyp6a8NP_523749.2 p450 39..503 CDD:278495 133/485 (27%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C45460971
Domainoid 1 1.000 151 1.000 Domainoid score I1386
eggNOG 1 0.900 - - E2759_KOG0158
Homologene 00.000 Not matched by this tool.
Inparanoid 1 1.050 161 1.000 Inparanoid score I1621
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D264519at33208
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 1 1.000 - - otm3438
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - P PTHR24292
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 1 1.000 - - X40
98.900

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