DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp28a5 and Cyp6a16

DIOPT Version :9

Sequence 1:	NP_609694.1	Gene:	Cyp28a5 / 34817	FlyBaseID:	FBgn0028940	Length:	505	Species:	Drosophila melanogaster
Sequence 2:	NP_001285631.1	Gene:	Cyp6a16 / 19836250	FlyBaseID:	FBgn0031726	Length:	500	Species:	Drosophila melanogaster

Alignment Length:	487	Identity:	137/487 - (28%)
Similarity:	242/487 - (49%)	Gaps:	41/487 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 TLTLVSLVVGLLYAVLVWNYDYWRKRGVPGPKPKLLCGNYPNMFTMKRHAIYDLDDIYRQYKNKY 69
            ||.|::.::..|...|.:.:.||..||:|..:|..|.|::..:.::  |....|.:.|..::...
  Fly     4 TLLLLTSLLSFLLGYLRYRFTYWELRGIPQLRPHFLFGHFFRLQSV--HYSELLQETYDAFRGSA 66

  Fly    70 DAVGIFGSRSPQLLVINPALARRVFVSNFKN------FHDNEIAKNIDEKTDFIFANNPFSLTGE 128
            ...|.:....|..:|::..|.:.|.:.:|.|      ||.:.:..|:            |:|.||
  Fly    67 KVAGTYVFLRPMAVVLDLDLVKAVLIRDFNNFVDRRSFHGDPLTANL------------FNLQGE 119

  Fly   129 KWKTRRADVTPGLTMGRIKTVYPVTNKVCQKLTEWVEKQLRLGSKDGIDAKH-MSLCFTTEMVTD 192
            :|:..|..::|..|.|::|.::...:.|.|:|....::  .:||:..:...| :...:||:::..
  Fly   120 EWRNLRTKLSPTFTSGKMKYMFGTVSTVAQQLGGTFDE--LVGSQGAVLELHDLMARYTTDVIGS 182

  Fly   193 CVLGLGAESFSDKPTPIMSKINDLFNQPWTFVLFFILTSSFPSLSHLIKL----RFVPVDVERFF 253
            |..|....|..:...........:|......:.:.|...::  ||.|.||    |.:..|:.:||
  Fly   183 CAFGTECSSLREPQAEFRQVGRRIFRNSNRSIRWRIFKMTY--LSSLAKLGLPVRILHPDITKFF 245

  Fly   254 VDLMGSAVETRRAQLAAGKQFERSDFLDYILQLGEKRN---LDNRQLLAYSMTFLLDGFETTATV 315
            ..::...||.|..:     ...|:||:|.:|.|..:.|   |...|:.|.:..|.:.||||:::.
  Fly   246 NRIVRETVELRERE-----NIRRNDFMDLLLDLRRQENGKGLTMEQMAAQAFVFFVAGFETSSSN 305

  Fly   316 LAHILLNLGRNKEAQNLLREEIRSHL-QDGTIAFEKLSDLPYLDACVQETIRLFPPGFMSNKLCT 379
            :::.|..|.:|::.|..||.||...: :.|.:.:|.:.::||||..:.||:|.:|......:|.:
  Fly   306 MSYALFELAKNQDVQQKLRMEINDSIGKHGKLTYEAMMEMPYLDQTITETLRKYPALSSLTRLAS 370

  Fly   380 ESIEIPNKEGPN-FVVEKGTTVVVPHYCFMLDEEFFPNPQSFQPERFLEPDAAKTFRERGVFMGF 443
            |..|||:.:|.: .|:||||:|.:|......|.|.:|.|..|:|||| .|||.:. |....|:||
  Fly   371 EDYEIPSPDGGDPVVLEKGTSVHIPVLAIHYDPEVYPEPHEFRPERF-APDACRE-RHPTAFLGF 433

  Fly   444 GDGPRVCIGMRFATVQIKAAIVELISKFNVKI 475
            |||||.|||:||..:|:|..::.|:.:|...:
  Fly   434 GDGPRNCIGLRFGRMQVKVGLITLLRRFRFSL 465

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp28a5	NP_609694.1	p450	33..500	CDD:299894	128/459 (28%)
Cyp6a16	NP_001285631.1	p450	32..492	CDD:278495	128/459 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	151	1.000	Domainoid score	I1386
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	161	1.000	Inparanoid score	I1621
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D264519at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm3438
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24292
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X40
	7	7.070