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Protein Alignment Cyp28a5 and Ptgis

DIOPT Version :9

Sequence 1:	NP_609694.1	Gene:	Cyp28a5 / 34817	FlyBaseID:	FBgn0028940	Length:	505	Species:	Drosophila melanogaster
Sequence 2:	NP_032994.1	Gene:	Ptgis / 19223	MGIID:	1097156	Length:	501	Species:	Mus musculus

Alignment Length:	559	Identity:	111/559 - (19%)
Similarity:	207/559 - (37%)	Gaps:	150/559 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 LVSLVVGLLYAVLVWNYDYWRKRGVPGPKPKLLCGNYPNMFTMKRHAI---YDLDDIYRQYKNKY 69
            |:.|:..||..:|:.:    |:|.....:|.|..|:.|.:    .||:   .|......:.|.|:
Mouse     6 LLGLLAVLLLLLLLLS----RRRARRPGEPPLDLGSIPWL----GHALEFGRDAASFLTRMKEKH 62

  Fly    70 DAV--GIFGSRSPQLLV-----------------INP---ALARRVFVSNFKNFHDNE------- 105
            ..:  .:.|.|...:|:                 .:|   .|..|:|.....||:.:|
Mouse    63 GDIFTVLVGGRYVTVLLDPHSYDTVVWELRTRLDFHPYAIFLMERIFDLQLPNFNPSEEKARMKP 127

  Fly   106 --IAKNIDEKTDFIFANNPFSLTGEKWKTRRADVTPG---------LTMGRIKTVYPVTNKVCQK 159
              :.:::...|:.::.|....|.|:..:........|         |:.|.: |:|
Mouse   128 TLMHRDLQALTEAMYTNLRTVLLGDSTEAGSGWQETGLLEFSYNALLSAGYL-TLY--------- 182

  Fly   160 LTEWVEKQLRLGSKDGIDAKHMSLCFTTEMVTDCV---LGLGAESFSDKPTPIMSKINDLFNQPW 221
               .||...|.......|..|.:..|.|....|.:   |..|:.|..||......|     |:.|
Mouse   183 ---GVEASPRTHESQAQDRVHSADVFHTFRQLDLLLPKLARGSLSAGDKDHACSVK-----NRLW 239

  Fly   222 TFVLFFILTSSFPSLSHLIKLRFVPVDVERFFVDLMGSAVETRRAQLAAGKQFERSDFLD----Y 282
            ..:                                       ..|:||:  :.:||.:|:    :
Mouse   240 KLL---------------------------------------SPARLAS--RADRSSWLESYLRH 263

  Fly   283 ILQLGEKRNLDNRQLLAYSMTFLLDGFETTAT------VLAHILLNLGRNKEAQNLLREEIRSHL 341
            :.::|....:..|.|:          .:..||      ....:||.|.:|.||...:|.|::..:
Mouse   264 LEEMGVSEEMQARALV----------LQLWATQGNMGPTAFWLLLFLLKNPEALAAVRAELKHTV 318

  Fly   342 --------QDGTIAFEKLSDLPYLDACVQETIRLFPPGFMSNKLCTESIEIPNKEGPNFVVEKGT 398
                    |..|:..:.|..:|.||:.:.||:||....|::.::..: :.:|..:|..|.:.:|.
Mouse   319 WQAEQPVSQMTTLPQKILDSMPVLDSVLNETLRLTAAPFITREVMAD-LALPMADGREFSLRRGD 382

  Fly   399 TVVV-PHYCFMLDEEFFPNPQSFQPERFLEPDAA--KTF-----RERGVFMGFGDGPRVCIGMRF 455
            .::: |......|.|.:..|:.|:..|||.||.:  |.|     |.:...|.:|.|...|:|..:
Mouse   383 RLLLFPFLSPQKDPEIYTEPEVFKYNRFLNPDGSEKKDFYKDGKRLKNYNMPWGAGHNQCLGKSY 447

  Fly   456 ATVQIKAAIVELISKFNVKINDKTRKDNDYEPGQIITGL 494
            |...||..:|.|::.|::::..:..:..:::..:...||
Mouse   448 AINSIKQFVVLLLTHFDLELGSEDTEVPEFDLSRYGFGL 486

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.