Protein Alignment Cyp28a5 and cyp-25A1

DIOPT Version :10

• Sequence 1: NP_609694.1
• Gene: Cyp28a5 / 34817
• FlyBaseID: FBgn0028940
• Length: 505
• Species: Drosophila melanogaster
• Sequence 2: NP_497775.3
• Gene: cyp-25A1 / 183247
• WormBaseID: WBGene00007963
• Length: 502
• Species: Caenorhabditis elegans
• Alignment Length: 502
• Identity: 121/502 - (24%)
• Similarity: 219/502 - (43%)
• Gaps: 61/502 - (12%)

  Fly     1 MVLITLTLVSLVVGLLYAVLV--WNYDYWRKRGVPGPKPKLLCGNYPNMFTMKRHAIYD-----L 58
            :::::..::|:....:|.:|.  ..:....|.|:.||:|....||.......|....||     .
 Worm     3 LLILSSLVISIFTFFIYIILARRERFKLREKIGLSGPEPHWFLGNLKQTAERKEKLGYDDANRWF 67

  Fly    59 DDIYRQYKNKYDAVGIFGSRSPQLLVINPALARRVFVSNFKNFHDNEIAK--NIDEKTDFIFANN 121
            ::::.||...:   ||:......:::.|....:.||:.||.||.|..:..  ..::.|..:..|:
 Worm    68 NELHEQYGETF---GIYYGSQMNIVISNEKDIKEVFIKNFSNFSDRSVPSIYEANQLTASLLMNS 129

  Fly   122 PFSLTGEKWKTRRADVTPGLTMGRIKTVYPVTNKVCQKLTEWVEKQLRLGSKDGIDAKHMSLCFT 186
            ..|    .||..|:.:.|..:.|::|.:....|.......:.:.::...|.|..|......|  |
 Worm   130 YSS----GWKHTRSAIAPIFSTGKMKAMQETINSKVDLFLDILREKASSGQKWDIYDDFQGL--T 188

  Fly   187 TEMVTDCVLGLGAESFSDKPTPIMSKINDLF---------NQPWTFVLFFILTSSFPSLSHLIK- 241
            .:::..|...:.:....|:        ||:|         |...........:...|.||...|
 Worm   189 LDVIGKCAFAIDSNCQRDR--------NDVFYVNAKKYISNIDIRHSKIIAASVLLPELSTFWKA 245

  Fly   242 -LRFVPV-DVERFFVDLMGSAVETRRAQLAAGKQFERSDFLDYILQLGEKRN--LDNRQLLAYSM 302
             .::.|: |.|...|:.:.:..|.||    .|:..:..|.|..:|...:.::  :..::::....
 Worm   246 LYKYTPLADAEIPLVEGLSNVYERRR----GGEGSDSVDLLKLLLNREDDKSKPMTKQEVIENCF 306

  Fly   303 TFLLDGFETTATVLAHILLNLGRNKEAQNLLREEIRSHLQDGTIAFEKLSDLPYLDACVQETIRL 367
            .|||.|:|||:|.:.:....|.:....|..|.|||....::|.:.::.:.::.|||...:||:|.
 Worm   307 AFLLAGYETTSTAMTYCSYLLSKYPNVQQKLYEEIMEAKENGGLTYDSIHNMKYLDCVYKETLRF 371

  Fly   368 FPPGF-MSNKLCTESIEIPNKEGPNFVVEKGTTVV-VPHYCFMLDEEFFPNPQSFQPERFLEPDA 430
            :||.. ...:||.|.|.|..:..|     ||..|| :||.... :.|.:.:|:.|.||||
 Worm   372 YPPVIHFIRRLCREDITIRGQFYP-----KGAIVVCLPHTVHR-NPENWDSPEEFHPERF----- 425

  Fly   431 AKTFRERG---VFMGFGDGPRVCIGMRFATVQIKAAIVELISKFNVK 474
             :.:.|:.   .::.||.|||.|:|||||.::.|..||:|:..|.:|
 Worm   426 -ENWEEKSSSLKWIPFGVGPRYCVGMRFAEMEFKTTIVKLLDTFELK 471

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp28a5	NP_609694.1	CYP6-like	67..499	CDD:410679	106/429 (25%)
cyp-25A1	NP_497775.3	CYP3A-like	73..495	CDD:410678	108/432 (25%)