DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp28a5 and cest-32

DIOPT Version :9

Sequence 1:	NP_609694.1	Gene:	Cyp28a5 / 34817	FlyBaseID:	FBgn0028940	Length:	505	Species:	Drosophila melanogaster
Sequence 2:	NP_504397.1	Gene:	cest-32 / 178909	WormBaseID:	WBGene00016862	Length:	545	Species:	Caenorhabditis elegans

Alignment Length:	332	Identity:	57/332 - (17%)
Similarity:	109/332 - (32%)	Gaps:	104/332 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly    57 DLDDIYRQYK----NKYDAVGIFGSRSPQLLVINPALARRVFVSNFKNFHDNEIAKNIDE----- 112
            |.:.:...||    :|:.....|..::...|...|            ||..:...|..||
Worm   267 DSESLLEWYKSQPLSKFQETATFEKKASGFLTFIP------------NFDGDFFPKPFDELSREA 319

  Fly   113 -KTDFIFANNPFSLTG--EKWKTRRADVTPGLTMGRIKTVY---PVTN--KVCQKLTEWVEKQLR 169
             |.|.:...:.:...|  ..:::||.|      |..||:.:   .|.|  .|.:::.|:..|.:.
Worm   320 PKLDAMATVDEYEGLGFLTMFQSRRND------MDIIKSSFGSDVVENAVDVQKRIMEFYMKNID 378

  Fly   170 LGSKDGIDAKHMSLCFTTEMVTDCVLGLGAESFSDKPTPIMSK--------INDLFNQPWTFVLF 226
            ......::.:      ..::::|....:||.......|...|.        .|...|.|:.....
Worm   379 KNDDKAVEKR------LIQLISDSWFNIGALETVKTSTKYGSNAYLGSFDYYNMGSNDPYATWFP 437

  Fly   227 FILTSSFPSLSHLI---KLRFVPVDVERFFVDLMGSAVETRRAQLAAGKQFERSDFLDYILQLGE 288
            |...:....|.:::   ..:|.|::.|...:|:||:..               ::|:.|    |.
Worm   438 FKAANHGSELKYMLGEGMGKFSPIEEEFKVIDMMGTLT---------------ANFVKY----GN 483

  Fly   289 KRNLDNRQL-------LAYSMTFLLDGFETTATVLAHILLNLGRNKEAQNLLREEIRSHLQDGTI 346
            ...::..:|       ..||. |.:|                        ..:.|:|.:.|||.:
Worm   484 PNGINGPELWKKYTPEKPYSY-FKID------------------------YPKSEMRDNFQDGRL 523

  Fly   347 -AFEKLS 352
             .||.::
Worm   524 KLFEDIN 530

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp28a5	NP_609694.1	p450	33..500	CDD:299894	57/332 (17%)
cest-32	NP_504397.1	COesterase	15..516	CDD:278561	51/316 (16%)
cest-32	NP_504397.1	Aes	<104..>227	CDD:223730
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D264519at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010