Protein Alignment Cyp28a5 and Cyp3a9

DIOPT Version :10

• Sequence 1: NP_609694.1
• Gene: Cyp28a5 / 34817
• FlyBaseID: FBgn0028940
• Length: 505
• Species: Drosophila melanogaster
• Sequence 2: NP_671739.2
• Gene: Cyp3a9 / 171352
• RGDID: 708392
• Length: 503
• Species: Rattus norvegicus
• Alignment Length: 496
• Identity: 137/496 - (27%)
• Similarity: 243/496 - (48%)
• Gaps: 74/496 - (14%)

  Fly     6 LTLVSLVVGLLYAVLVWNYDYWRKRGVPGPKPKLLCGNYPNMFTMKRHAIYDLDDIYRQYKNKYD 70
            |.::|||  |||.....::..::|.|:|||||....|.    ....|...::.|   :....||.
  Rat    14 LLVISLV--LLYLYGTHSHGIFKKLGIPGPKPLPFLGT----ILAYRKGFWEFD---KYCHKKYG 69

  Fly    71 AV-GIFGSRSPQLLVINPALARRVFV-------SNFKNFHDNEIAK---NIDEKTDFIFANNPFS 124
            .: |::..|.|.|.:.:|.:.:.|.|       :|.:||....|.|   :|.|
  Rat    70 KLWGLYDGRQPVLAITDPDIIKTVLVKECYSTFTNRRNFGPVGILKKAISISE------------ 122

  Fly   125 LTGEKWKTRRADVTPGLTMGRIKTVYPVTNKVCQKLTEWVEKQLRLGSKDG--IDAKHMSLCFTT 187
              .|:||..||.::|..|.|::|.::|:.|    :.|:.:.:.:|.||::|  ...|.:...::.
  Rat   123 --DEEWKRIRALLSPTFTSGKLKEMFPIIN----QYTDMLVRNMRQGSEEGKPTSMKDIFGAYSM 181

  Fly   188 EMVTDCVLGLGAESFSDKPTPIMSKINDLFNQPWTFVLF---FILTSSFPSLSHL---IKLRFVP 246
            :::|....|:..:|.::...|.:.||..|..    |.:|   |:..:.||.|:.|   :.:...|
  Rat   182 DVITATSFGVNVDSLNNPQDPFVEKIKKLLK----FDIFDPLFLSVTLFPFLTPLFEALNVSMFP 242

  Fly   247 VDVERFFVDLMGSAVETRRAQLAAGKQFERSDFLDYILQLGEKRNLDNR------QLLAYSMTFL 305
            .||    :|...::||..:......|:.:|.|||..::.....:..|:.      :::|.|:.|:
  Rat   243 RDV----IDFFKTSVERMKENRMKEKEKQRMDFLQLMINSQNSKVKDSHKALSDVEIVAQSVIFI 303

  Fly   306 LDGFETTATVLAHILLNLGRNKEAQNLLREEIRSHLQDGTIA-FEKLSDLPYLDACVQETIRLFP 369
            ..|:|||::.|:.:|..|..:.:.|..|::||.:.|.:...| ::.|..:.|||..|.||:||:|
  Rat   304 FAGYETTSSALSFVLYLLAIHPDIQKKLQDEIDAALPNKAHATYDTLLQMEYLDMVVNETLRLYP 368

  Fly   370 PGFMSNKLCTESIEIPNKEGPNFV-VEKGTTVVVPHYCFMLDEEFFPNPQSFQPERFLE--PDAA 431
            ......::|...:||      |.| :.|||.|::|.:....|..::|.|:.|:||||.:  .|..
  Rat   369 IAGRLERVCKTDVEI------NGVFIPKGTVVMIPTFALHKDPHYWPEPEEFRPERFSKKNQDNI 427

  Fly   432 KTFRERGVFMGFGDGPRVCIGMRFATVQIKAAIVELISKFN 472
            ..:    :::.||:|||.|||||||.:.:|.|:|.::..|:
  Rat   428 NPY----MYLPFGNGPRNCIGMRFALMNMKVALVRVLQNFS 464

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp28a5	NP_609694.1	CYP6-like	67..499	CDD:410679	120/435 (28%)
Cyp3a9	NP_671739.2	CYP3A	67..492	CDD:410743	120/434 (28%)