Protein Alignment Cyp28a5 and Cyp3a59

DIOPT Version :9

• Sequence 1: NP_609694.1
• Gene: Cyp28a5 / 34817
• FlyBaseID: FBgn0028940
• Length: 505
• Species: Drosophila melanogaster
• Sequence 2: NP_001098630.1
• Gene: Cyp3a59 / 100041449
• MGIID: 3769707
• Length: 503
• Species: Mus musculus
• Alignment Length: 503
• Identity: 128/503 - (25%)
• Similarity: 237/503 - (47%)
• Gaps: 70/503 - (13%)

  Fly     7 TLVSLVVGLLYAVLVWNYDY--WRKRGVPGPKPKLLCGNYPNMFTMKRHAIYDLD-DIYRQYKNK 68
            |.|.||..|::..:...|.:  ::|.|:|||||..|.|...|.|    ..::..| |.|::|...
Mouse    11 TWVLLVTSLVFFYIYGTYSHGLFKKLGIPGPKPLPLFGTIFNYF----DGMWKFDEDCYKKYGKI 71

  Fly    69 YDAVGIFGSRSPQLLVINPALARRVFVSNFKNFHDNEIAKNIDEKTDFIFANNPF---------S 124
            :   |.:....|.|.:::|.:.:.|.|....:                :|.|.|.         |
Mouse    72 W---GFYVGPKPILAIMDPEIIKIVLVKECYS----------------VFTNRPTLGPVGFLKKS 117

  Fly   125 LT---GEKWKTRRADVTPGLTMGRIKTVYPVTNKVCQKLTEWVEKQLRLGSKDGIDAKHMSLCFT 186
            :|   .|:||..|..::|..|.|::|.::|:..:....|...:.::...|  :.|:.|.:...::
Mouse   118 ITISEDEEWKRLRTLLSPTFTSGKLKEMFPIMRQYGDILVRNLRREEEKG--EPINMKDIFGAYS 180

  Fly   187 TEMVTDCVLGLGAESFSDKPTPIMSKINDLFNQPWTFVLF--FIL-TSSFPSLS---HLIKLRFV 245
            .:::|....|:..:|.::...|.:.|...:..    |.:|  |:| |..||.|:   .::.|...
Mouse   181 MDVITGTSFGVNIDSLNNPQNPFVQKTKKILK----FKIFDPFLLSTILFPFLTPIYEMLNLSIF 241

  Fly   246 PVDVERFFVDLMGSAVETRRAQLAAGKQFERSDFLDYILQLGEKRN------LDNRQLLAYSMTF 304
            |.|...||...    |:..:.:..|.||..|.|||..::.....:.      |.:.::.|.::.|
Mouse   242 PRDSMNFFKKF----VKRMKKERLASKQKNRVDFLQLMMNTQNSKGQESQKALSDLEMAAQAVIF 302

  Fly   305 LLDGFETTATVLAHILLNLGRNKEAQNLLREEI-RSHLQDGTIAFEKLSDLPYLDACVQETIRLF 368
            :..|::.|:|.::.|:..|..:.:.|..|::|| |:......:.::.|.|:.|||..|.|::||:
Mouse   303 IFGGYDATSTSISLIMYELATHPDVQKKLQDEIDRTLPNKAPVTYDALMDMEYLDMVVNESLRLY 367

  Fly   369 PPGFMSNKLCTESIEIPNKEGPNFV-VEKGTTVVVPHYCFMLDEEFFPNPQSFQPERFLEPDAAK 432
            |......::..:.:||      |.| :.|||.|::|.|....:.|::|.||.|.|.||.:.:...
Mouse   368 PTAIRLERVSKKDVEI------NGVFIPKGTVVMIPIYPLHRNPEYWPEPQEFCPGRFSKENEGN 426

  Fly   433 TFRERGVFMGFGDGPRVCIGMRFATVQIKAAIVELISKFNVKINDKTR 480
            .  :..::|.||:|||.|:.||||.:.:|.|::.::..|.|:..::|:
Mouse   427 I--DPYIYMPFGNGPRNCLDMRFALISMKLAVIGVLQNFTVQPCEETQ 472

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp28a5	NP_609694.1	p450	33..500	CDD:299894	120/475 (25%)
Cyp3a59	NP_001098630.1	p450	39..493	CDD:278495	120/475 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0158
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D264519at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X40
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.820