Protein Alignment NimC1 and Egfem1

DIOPT Version :9

• Sequence 1: NP_001260453.1
• Gene: NimC1 / 34816
• FlyBaseID: FBgn0259896
• Length: 622
• Species: Drosophila melanogaster
• Sequence 2: XP_006535622.1
• Gene: Egfem1 / 75740
• MGIID: 1922990
• Length: 658
• Species: Mus musculus
• Alignment Length: 623
• Identity: 142/623 - (22%)
• Similarity: 197/623 - (31%)
• Gaps: 245/623 - (39%)

  Fly    31 CSHPE-SVPYNRKVLKSKLVPFQQYSYFHGWVTKYRHQYVYEDETAYRTVMRPSCCEGYEGSVE- 93
            ||.|. .|.|.|::           .|:    ..|||.|..|.:|.:|      ||.|:   ::
Mouse   102 CSGPRWCVGYERRI-----------RYY----IIYRHVYATEHQTVFR------CCPGW---IQW 142

  Fly    94 NCKPVCRQQCPQHGF------CSSPNT--CSCNAGYGGIDCHPVCPTVCGKNEFCDRPGVCSCQN 150
            :.:|.|.......|.      ||..:|  |.|:.|:.|..|.      ...||       |:..|
Mouse   143 DDEPGCFSSLSSLGTHFSGRECSYQDTRQCLCSQGFHGPHCQ------YDINE-------CAVDN 194

  Fly   151 GYKRTSPSDNCLPVCEKECGHHSFCSEPGK--CECEPG--YEKVGNGTVFPDGYKNNSNGNCSPI 211
            |            .|...|     |:..|.  |.|:.|  .|:.|.|....|... ..||.|...
Mouse   195 G------------GCRDRC-----CNTIGSYYCRCQAGQKLEEDGRGCEDVDECA-VVNGGCQQR 241

  Fly   212 CPKDCGQNSRCVRPGVCECENGYA--GDD---------------GGTNCRPVCSTCPENGLCLSP 259
            |....|...       |||:.||.  .|:               |...|..:|.|  |||:..
Mouse   242 CINTLGTFH-------CECDTGYRRHADERTCIISFLSETDPCAGANGCAHLCQT--ENGMAR-- 295

  Fly   260 GVCVCKPGYVMRNDLCQPHCE---KCSDNA-----HCVAPN---QCECFPGYESSGADKK-C--- 309
              |.|..||.:..|  :..||   :|::..     |||...   .|.|.||:| .|||:| |
Mouse   296 --CACHAGYQLSED--KKACEDINECAEELAPCAHHCVNSKGSFTCTCHPGFE-LGADRKHCYRI 355

  Fly   310 ----VPKCSKGCTNGFCFAPETCVCSIGYQMGPNQVCEPKCSLNCVHGKCTSPETCTCDPGYRFK 370
                |..|.|  .||.|                :..|||  ::...|        |:|:.|::.
Mouse   356 ELEIVNICEK--NNGGC----------------SHHCEP--AIGGAH--------CSCNHGHQL- 391

  Fly   371 DNSHHECDPI--CDSG--CSNGHCVAPNF-----CICHDGYQLNSTNPVTSMCQPICKGCQFGDC 426
            |.....|...  |:||  |....|:  |:     |.|.:|:|::|..
Mouse   392 DTDGKTCIDFDECESGEACCAQLCI--NYLGGYECSCEEGFQISSDG------------------ 436

  Fly   427 VAPNVCECNVGYENINGLCE-----------LQTTTDSYEYSTTTVELQSSTVDPQLQTSTSEVP 480
                 |.|:...|.:....|           .|.....:.|           :||.|..|..:
Mouse   437 -----CGCDALDEQLEEEEEEIDILRFPGRLAQNPPQPFPY-----------LDPSLTASYED-- 483

  Fly   481 HSNCTAGCMCWIEYDGM----------GTFNTAKCAKICVDPQDKPCLNLDNCQ-------CDLS 528
            ..|..|......|..|:          |||. ..|:..|.|     |:|...||       |...
Mouse   484 EDNDDADSEAEGEVQGLTALYRVVCLDGTFG-LDCSLSCED-----CMNGGRCQEGKSGCLCPAE 542

  Fly   529 SGQLVCQEDSDM--------------DYSGENSRYVCH 552
            ...|:|.|.|.:              .:.|:|.:..||
Mouse   543 WTGLICNESSVLRTGEDQQAPAGCLKGFFGKNCKRKCH 580

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
NimC1	NP_001260453.1	None
Egfem1	XP_006535622.1	EMI	71..140	CDD:369419	17/61 (28%)
		FXa_inhibition	190..225	CDD:373209	12/51 (24%)
		vWFA	<213..265	CDD:381780	16/59 (27%)
		vWFA	<268..310	CDD:381780	12/49 (24%)
		vWFA	<308..350	CDD:381780	14/42 (33%)
		FXa_inhibition	363..398	CDD:373209	13/63 (21%)
		vWFA	<395..436	CDD:381780	12/42 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1218
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900