Protein Alignment NimC1 and Pear1

DIOPT Version :9

• Sequence 1: NP_001260453.1
• Gene: NimC1 / 34816
• FlyBaseID: FBgn0259896
• Length: 622
• Species: Drosophila melanogaster
• Sequence 2: NP_001027585.1
• Gene: Pear1 / 73182
• MGIID: 1920432
• Length: 1034
• Species: Mus musculus
• Alignment Length: 852
• Identity: 204/852 - (23%)
• Similarity: 274/852 - (32%)
• Gaps: 371/852 - (43%)

  Fly    29 NDCSHPESVPYNRKVLKSKLVPFQ---QYSYFHGWV---TKYRHQYVYEDETAYRTVM----RP- 82
            |.|:..||.....|  :|.|.||.   ..|....|.   |..:...||  .|.||.|:    ||
Mouse    25 NVCTFWESFTTTTK--ESHLRPFSLLPAESCHRPWEDPHTCAQPTVVY--RTVYRQVVKMDSRPR 85

  Fly    83 -SCCEGYEGSVENCKPVCRQQCPQHGFCSSPNTCSCNAGYGGIDCHPVC-PTV----------CG 135
             .||.||..|...|.|:|.|:| .||.|.:||.|.|..|:.|.||...| |.:          ||
Mouse    86 LQCCRGYYESRGACVPLCAQEC-VHGRCVAPNQCQCAPGWRGGDCSSECAPGMWGPQCDKFCHCG 149

  Fly   136 KNEFCD-RPGVCSCQNGYKRTSPSDNCL---------PVCEKECGHHSFCSEP------------ 178
            .|..|| :.|.|.|.:|.:    ..|||         |.|:.:|..:....:|
Mouse   150 NNSSCDPKSGTCFCPSGLQ----PPNCLQPCPAGHYGPACQFDCQCYGASCDPQDGACFCPPGRA 210

  Fly   179 ---------------------------------GKCECEPGYEKVGNGTVFPDGYKNNS------ 204
                                             |.|.|.||:..|......|:|:...:
Mouse   211 GPSCNVPCSQGTDGFFCPRTYPCQNGGVPQGSQGSCSCPPGWMGVICSLPCPEGFHGPNCTQECR 275

  Fly   205 --NG----------NCSP---------ICPK-----------DCGQNSRCV-RPGVCECENGYAG 236
              ||          :|:|         .||.           ||...:||. ..|.|.||:|:.|
Mouse   276 CHNGGLCDRFTGQCHCAPGYIGDRCQEECPVGRFGQDCAETCDCAPGARCFPANGACLCEHGFTG 340

  Fly   237 D--------DG--GTNCRPVCSTCPENGLCLSP--GVCVCKPGYV-----------MRNDLCQPH 278
            |        ||  |.:|:..|:..||:.|...|  |.|.|:||:.           .....||.|
Mouse   341 DRCTERLCPDGRYGLSCQEPCTCDPEHSLSCHPMHGECSCQPGWAGLHCNESCPQDTHGPGCQEH 405

  Fly   279 CEKCSDNAHCVAPN-QCECFPGYESSGADKKCVP-----KCSK--GCTNGFCFAP--ETCVCSIG 333
            | .|.....|:|.: .|.|.|||........|.|     .||.  .|.|....:|  .||:|..|
Mouse   406 C-LCLHGGLCLADSGLCRCAPGYTGPHCANLCPPDTYGINCSSRCSCENAIACSPIDGTCICKEG 469

  Fly   334 YQMGPNQV----------CEPKCSLNCVHGKCTSPET--CTCDPGYR------------------ 368
            :|.|...|          |...|  .|.|....||:|  |||.||:.
Mouse   470 WQRGNCSVPCPLGTWGFNCNASC--QCAHDGVCSPQTGACTCTPGWHGAHCQLPCPKGQFGEGCA 532

  Fly   369 -FKDNSHHE-CDPI-----CDSG------------------CSN-------GHCVAPN-FCICHD 400
             ..|..|.: |||:     |.:|                  |||       |.||:.| .|:|..
Mouse   533 SVCDCDHSDGCDPVHGQCRCQAGWMGTRCHLPCPEGFWGANCSNTCTCKNGGTCVSENGNCVCAP 597

  Fly   401 GYQLNSTNPVTSMCQPICKGCQFGD-CVAPNVCECNVGYENI---NGLCELQTTTDSYEYSTTTV 461
            |::..|       ||..|...::|. ||.   |:||..:.:.   :|.|
Mouse   598 GFRGPS-------CQRPCPPGRYGKRCVQ---CKCNNNHSSCHPSDGTC---------------- 636

  Fly   462 ELQSSTVDPQLQTSTSEVPHSNCTAGCMCWIEYD----------GMGTFNTAKCAKIC------- 509
                                 :|.||   |...|          |:      ||:::|
Mouse   637 ---------------------SCLAG---WTGPDCSEACPPGHWGL------KCSQLCQCHHGGT 671

  Fly   510 VDPQDKPCL---------------------NLDN-CQCDLSSGQLVCQEDSDMDYSGENSRYVCH 552
            ..|||..|:                     |... |||||                ||    :||
Mouse   672 CHPQDGSCICTPGWTGPNCLEGCPPRMFGVNCSQLCQCDL----------------GE----MCH 716

  Fly   553 ILPEQGA------RSEAEVRIPDRTGSSNKWMI-----IVGSCAGMIIGVA----------ATII 596
              ||.||      .|.|:.::    ||...:.|     :..:..|.:||:|          |..|
Mouse   717 --PETGACVCPPGHSGADCKM----GSQESFTIMPTSPVTHNSLGAVIGIAVLGTLVVALIALFI 775

  Fly   597 GIKYYRR 603
            |.:.:::
Mouse   776 GYRQWQK 782

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
NimC1	NP_001260453.1	None
Pear1	NP_001027585.1	EMI	25..93	CDD:284877	23/71 (32%)
		EGF_CA	535..580	CDD:304395	10/44 (23%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	823..883
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	925..1034

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1218
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810