Protein Alignment NimC1 and Megf6

DIOPT Version :10

• Sequence 1: NP_001260453.1
• Gene: NimC1 / 34816
• FlyBaseID: FBgn0259896
• Length: 622
• Species: Drosophila melanogaster
• Sequence 2: NP_075244.1
• Gene: Megf6 / 65049
• RGDID: 621188
• Length: 1574
• Species: Rattus norvegicus
• Alignment Length: 840
• Identity: 194/840 - (23%)
• Similarity: 260/840 - (30%)
• Gaps: 314/840 - (37%)

  Fly    10 FVCLSLSF--------------GTSFAILRHGLNDCSHPESVPYNRKVLKSKLVPFQQYSYFHGW 60
            ||||..||              ||.|.    |.:.|..||                       ||
  Rat   513 FVCLDHSFGHDCSLTCDDCRNGGTCFP----GQDGCDCPE-----------------------GW 550

  Fly    61 VTKYRHQYVYEDETAYRTVMRPSC---CEGYEGSVENCKPV--------------CRQQCPQHGF 108
            ..      :..:||........:|   |....|.  .|.||              |...||: ||
  Rat   551 TG------IICNETCPPDTFGKNCSSPCTCQNGG--TCDPVLGACRCPPGVSGAHCEDGCPK-GF 606

  Fly   109 --------CSSPN---------TCSCNAGYGGIDCHPVCP-----TVCGKNEFCD---------R 142
                    |...|         .|.|:.|..|..||..||     ..|.::..|:         :
  Rat   607 YGKHCRKKCHCANRGRCHRLYGACLCDPGLYGRFCHLACPPWAFGPGCSEDCLCEQSHTRSCNPK 671

  Fly   143 PGVCSCQNGYKRTSPSDNCLPVCEK-----ECGHHSFCS-----EP--GKC--ECEPGYEKVGNG 193
            .|.|||:.|::    .:.|...||.     .|.|...|.     :|  |:|  :|.|||:....|
  Rat   672 DGSCSCKAGFQ----GERCQAECESGFFGPGCRHRCTCQPGVACDPVSGECRTQCPPGYQGEDCG 732

  Fly   194 TVFPDG-YKNNSNGNCSPICPKDCGQNSRCVR-PGVCECENGYAGDDGGTN---------CRPVC 247
            ...|.| :..|.:|:||.:       .:.|.| .|.|.|..|..|:|.|.:         |:.:|
  Rat   733 QECPVGTFGVNCSGSCSCV-------GAPCHRVTGECLCPPGKTGEDCGADCPEGRWGLGCQEIC 790

  Fly   248 STCPENGLCLSP--GVCVCKPGYVMRNDLCQPHCE------------KCSDNAHC-VAPNQCECF 297
            ..| |:|...:|  |.|:|.||:|  ...||..|.            .|:::.|| ....:|.|.
  Rat   791 PAC-EHGASCNPETGTCLCLPGFV--GSRCQDTCSAGWYGTGCQIRCACANDGHCDPTTGRCSCA 852

  Fly   298 PGYESSGADKKC-----VPKCSKGCT----NGFCFAPE-TCVCSIGYQ------------MGPNQ 340
            ||:......:.|     .|.|...|.    :|.|.|.. .|:|..||:            .||:
  Rat   853 PGWTGLSCQRACDSGHWGPDCIHPCNCSAGHGNCDAVSGLCLCEAGYEGPRCEQSCRQGYYGPS- 916

  Fly   341 VCEPKCSLNCVHGKCTS--PETCTCDPGYRFKDNSHHECDPI------CDSGCS----------N 387
             ||.||  .|.||....  ...|||..|:| .....|.| |.      |||.|:          .
  Rat   917 -CEQKC--RCEHGAACDHVSGACTCPAGWR-GSFCEHAC-PAGFFGLDCDSACNCSAGAPCDAVT 976

  Fly   388 GHCVAP----------------------NFCICHDGYQLNSTNPVTSMCQ-------PIC----- 418
            |.|:.|                      ..|.|.:|...:|   ||..|.       |.|
  Rat   977 GSCICPAGRWGPRCAQSCPPLTFGLNCSQICTCFNGASCDS---VTGQCHCAPGWMGPTCLQACP 1038

  Fly   419 -----KGCQ--------------FGDCVAPN-----VC--ECNVGYE----NIN------GLCEL 447
                 |.||              .|.|..|.     .|  ||..|:.    .:|      |:|:.
  Rat  1039 PGLYGKNCQHSCLCRNGGRCDPILGQCTCPEGWTGLACENECLPGHYAAGCQLNCSCLHGGICDR 1103

  Fly   448 QTTTDSYEYSTTTVELQSSTVDPQLQTSTSEVPHSNC---------TAGCMCWIEYDG------- 496
            .|.........|..:.|||.|.........|  |..|         |..|.|...:.|
  Rat  1104 LTGHCLCPAGWTGDKCQSSCVSGTFGVHCEE--HCACRKGASCHHVTGACFCPPGWRGPHCEQAC 1166

  Fly   497 -MGTFNTAKCAKICVDPQDKPCLNL-DNCQCDLSSGQLVCQEDSDMDYSGENSRYVCHILPEQGA 559
             .|.|..| ||:.|:.|.:..|.:: ..|:|......|.|::.......|::..::|....|..|
  Rat  1167 PRGWFGEA-CAQRCLCPTNASCHHVTGECRCPPGFTGLSCEQACQPGTFGKDCEHLCQCPGETWA 1230

  Fly   560 RSEAEVRIPDRTGSSNKWMIIVGSCAGMIIGVAATIIGIKYYRRSTSRRNFEAEEAIVEC 619
            ...|.                 |.|.     .||...|....:|..|.|.....|.|.:|
  Rat  1231 CDPAS-----------------GVCT-----CAAGYHGTGCLQRCPSGRYGPGCEHICKC 1268

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
NimC1	NP_001260453.1	None
Megf6	NP_075244.1	EMI	41..113	CDD:462204
		FXa_inhibition	127..162	CDD:464251
		vWFA	<154..202	CDD:469594
		FXa_inhibition	209..245	CDD:464251
		vWFA	<237..285	CDD:469594
		vWFA	<284..325	CDD:469594
		FXa_inhibition	338..373	CDD:464251
		vWFA	<371..410	CDD:469594
		vWFA	<413..452	CDD:469594
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1555..1574