Protein Alignment NimC1 and pear1

DIOPT Version :10

• Sequence 1: NP_001260453.1
• Gene: NimC1 / 34816
• FlyBaseID: FBgn0259896
• Length: 622
• Species: Drosophila melanogaster
• Sequence 2: XP_700533.4
• Gene: pear1 / 571812
• ZFINID: ZDB-GENE-091230-1
• Length: 1020
• Species: Danio rerio
• Alignment Length: 863
• Identity: 209/863 - (24%)
• Similarity: 278/863 - (32%)
• Gaps: 321/863 - (37%)

  Fly     6 FSLHFVC-LSLSFGTSFAILRHGLNDCSHPESVPYNRKVLKSKLVPFQQYS---YFHGWVTK--Y 64
            |.|..|| ||||...      ...|.||..||  :...|.:|...||.|.|   ....|...  .
Zfish    11 FVLGCVCELSLSLDP------RDPNVCSLWES--FTTSVKESYAQPFDQMSEEPCSEPWSANKCT 67

  Fly    65 RHQYVYEDETAYRTVM------RPSCCEGYEGSVENCKPVCRQQCPQHGFCSSPNTCSCN----- 118
            ||:..|  :|.||.|:      |..||.|:..|...|.|.|.::| .||.|.:|:.|.|.
Zfish    68 RHRITY--KTLYRQVVKMDYRRRYQCCPGFYESRNKCVPRCTKEC-VHGRCVAPDRCQCEMGWRG 129

  Fly   119 --------------------------------------AGYGGIDCHPVCPT-----------VC 134
                                                  |||.|..||..||.           .|
Zfish   130 DDCSSSCDGQHWGPGCRRLCECQNGGECDVLTGNCQCPAGYTGQHCHDPCPVKWFGQGCRQECQC 194

  Fly   135 GKNEFCDR-PGVCSCQNGYKRT---------------SPSDN---------CL-------PVCEK 167
            |....|:: .|.|.|:.|:..|               .|..|         ||       |||.:
Zfish   195 GTGGICNQTTGECVCKQGFTGTLCEESCPRPKRCAARCPCQNGGICQGNGVCLCPPGWMGPVCTE 259

  Fly   168 ECGHHSF---CS-------------EPGKCECEPGY------EKVGNGTVFPDGYKNNSNGNCSP 210
            .|....|   ||             |.|:|:|:.||      |:...||...|         |..
Zfish   260 RCPPGRFGINCSKDCLCHNGGHCDQEKGQCQCDAGYTGERCNEECPVGTYGED---------CKG 315

  Fly   211 ICPKDCGQNSRCVR-PGVCECENGYAGDD----------GGTNCRPVCSTCPENGLCLSP--GVC 262
            :|  ||...:||.. .|.|.||.|:.|..          .|.:|:..|...|.|.|...|  |.|
Zfish   316 VC--DCANGARCYNIHGGCLCEPGFKGPRCDHRMCPEAVFGMHCQHRCLCNPLNTLSCHPLKGEC 378

  Fly   263 VCKPGY--VMRNDLCQP--HCEKCSDNAHCV-------APNQCECFPGY---------ESSGADK 307
            .|:||:  :..|:.|..  :...|.:...||       ...||.|.||:         |.....|
Zfish   379 TCQPGWAGLYCNETCAQGYYGNGCLEPCLCVNGGVCDSVTGQCHCPPGFTGLHCEKLCEDGFYGK 443

  Fly   308 KCVPKCSKGCTNGFCFAP--ETCVCSIGYQMGPNQVCEPKCSLNCVHG----------KCT---- 356
            .|:..|.  |.|....:|  ..|:|..|:: ||:      ||:.|..|          |||
Zfish   444 GCLSACK--CVNSIVCSPVDGACICKEGWR-GPD------CSIACSEGTWGPGCNRTCKCTNGAS 499

  Fly   357 ---SPETCTCDPGYR------------FKDNSHHECDPICDSGCSN--GHCVAPNFCI------- 397
               :..:|.|..|:|            |.....::||.:.|.||.:  |.|:    |:
Zfish   500 CDPADGSCKCTAGWRGASCDEPCLIGTFGPGCQNQCDCVHDEGCESVTGQCL----CLPGWTGVR 560

  Fly   398 ----CHD---GYQLNST----NPVT----------------SMCQPICKGCQFGD--------CV 427
                |.:   |.|.|.|    |..|                :.||.:|....||:        ||
Zfish   561 CTQQCPEGTWGIQCNQTCSCLNSATCQAHTGTCLCKPGFWGAQCQHMCSAGLFGEKCSRHCPPCV 625

  Fly   428 APNV-------CECNVGYENINGLCELQTTTDSYEYSTTTVELQSSTVDPQLQTSTSEVPHSNCT 485
            ..:.       |:|..||  ...|||.......|....:.|...::..     |...||....|.
Zfish   626 HASSCHHITGDCQCLSGY--TGPLCEQACPVGRYGSHCSNVCRCTNNA-----TCHHEVGLCICP 683

  Fly   486 AGCMCWIEYD-----GMGTFNTAKCAKICVDPQDKPCLNLDNCQCDLSSGQLVCQEDSDMDYSGE 545
            ||   |...|     ..|||. ..||:.|..|        .|..||..:|..||:..     .||
Zfish   684 AG---WTGSDCSLLCQAGTFG-INCAQTCSCP--------PNHSCDPHNGDCVCEPG-----PGE 731

  Fly   546 NSRYVCHILPEQGARSEAEVRIPDRTGSSNKWMIIVGSCAGMIIGVAATIIGIKYYRRS------ 604
            ..:      |||    |..|.:|......:.|..|.|....:|:.|....:.:.|.||.
Zfish   732 ACK------PEQ----ELSVMVPVSPVERDSWGAIAGIVVLVILVVLLLAVLLLYRRRQQDKQSN 786

  Fly   605 ------TSRRNFEAEEAI 616
                  :|.|...:|.|:
Zfish   787 TPVVSFSSTRTVSSEYAV 804

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
NimC1	NP_001260453.1	None
pear1	XP_700533.4	EMI	28..97	CDD:462204	23/72 (32%)
		Laminin_EGF	411..451	CDD:395007	9/41 (22%)