DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment NimC1 and Dkk4

DIOPT Version :9

Sequence 1:	NP_001260453.1	Gene:	NimC1 / 34816	FlyBaseID:	FBgn0259896	Length:	622	Species:	Drosophila melanogaster
Sequence 2:	NP_001102802.1	Gene:	Dkk4 / 502097	RGDID:	1563172	Length:	221	Species:	Rattus norvegicus

Alignment Length:	227	Identity:	46/227 - (20%)
Similarity:	67/227 - (29%)	Gaps:	74/227 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly   208 CSPICP--------------KDCGQNSRCVRPGVCE----C-----ENGYAGDDGGTNCRPVCST 249
            |||:..              :..|:.|:||....|.    |     |..:.     ..||.|...
  Rat    13 CSPLGALVLDFNNIKSSSDVQGSGKGSQCVSDKDCNVGKFCFALHDERSFC-----ATCRRVRRR 72

  Fly   250 CPENGLCLSPGVCVCKPGYVMRNDLC------QPHCEKCSDNAHCVAPNQCECFPGYESSGADKK 308
            |..:.:|....|||        ||:|      :|..::.:|............:|..|:....|.
  Rat    73 CQRSAMCCPGTVCV--------NDVCTAVENTRPVMDRNTDGQDGTYAEGTTKWPAEENRPQGKP 129

  Fly   309 CVPK--CSKGCTNGFCFAPETCVCSIGYQMGP---------NQVCEP------KCSLNCVHGKCT 356
            ...|  .:||.....|.....|        ||         .::|:|      .||.........
  Rat   130 STKKSQSNKGQEGESCLRTSDC--------GPGLCCARHFWTKICKPVLLEGQVCSRRGHKDTAQ 186

  Fly   357 SPE---TCTCDPGYRFKD----NSHHECDPIC 381
            :||   .|.|.||...:.    |..|....:|
  Rat   187 APEIFQRCDCGPGLSCRSQVTGNRQHTRLRVC 218

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
NimC1	NP_001260453.1	None
Dkk4	NP_001102802.1	Dickkopf_N	41..91	CDD:282549	15/62 (24%)
Dkk4	NP_001102802.1	Prokineticin	<145..202	CDD:148298	14/64 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1218
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900