Protein Alignment NimC1 and pear1

DIOPT Version :10

• Sequence 1: NP_001260453.1
• Gene: NimC1 / 34816
• FlyBaseID: FBgn0259896
• Length: 622
• Species: Drosophila melanogaster
• Sequence 2: XP_017952446.2
• Gene: pear1 / 100489801
• XenbaseID: XB-GENE-6045593
• Length: 1087
• Species: Xenopus tropicalis
• Alignment Length: 883
• Identity: 207/883 - (23%)
• Similarity: 284/883 - (32%)
• Gaps: 355/883 - (40%)

  Fly    10 FVCLSLSFGTSFAILRHGLNDCSHPESVPYNRKVLKSKLVPFQQ---------YSYFHG------ 59
            ::.:.:.||.|.:  .:..|.||..||  :...|.:|...|:.|         ::||..
 Frog    12 WMLVQIQFGKSLS--PNDPNVCSFWES--FTLAVKESYTQPYSQLSPDSCDSSWNYFKACTPQKI 72

  Fly    60 -WVTKYRHQYVYEDETAYRTVMRPSCCEGYEGSVENCKPVCRQQCPQHGFCSSPNTCSCNAGYGG 123
             :.|.|||:...:    ||  .|..||:||..|.:.|.|.|.|:| .||.|.:|:.|.|..|:.|
 Frog    73 LYRTAYRHRVKLD----YR--RRYWCCKGYYESNDICVPRCTQEC-VHGRCIAPDQCQCEPGWRG 130

  Fly   124 IDCH---------PVCPTVCG--------------------KNEFCDRP---------------- 143
            .||.         |.|.:.|.                    ::.||::|
 Frog   131 KDCSSACEAHVWGPKCNSTCPCQNNGACDAASGTCICPPGFRDPFCEKPCDPGTYGGGCSLSCQC 195

  Fly   144 ----------GVCSCQNGY---------KRTSP-----SDNCLPVCEKECGHHSFCSE-PGKCEC 183
                      |.|.|..||         |...|     ||.||      |.....|:: .|:|.|
 Frog   196 KNGAECDPENGACLCPEGYTGPYCEIRCKEVQPANFSCSDQCL------CQSGGICNQSSGECSC 254

  Fly   184 EPGYEKVGNGTVFPDGY--KN-------NSNGNCSP------------------ICP-----KDC 216
            .||:.........||||  :|       ::.|.|.|                  .||     |||
 Frog   255 PPGWMGSLCSIPCPDGYYGRNCKQECLCHNGGQCDPKTGQCLCSEGYTGDHCREECPIGKYGKDC 319

  Fly   217 GQNSRCVRP-------GVCECENGYAGDDGGTN-CRPVCSTCPENGLCL-----------SPGVC 262
            .:...|:..       |.|.||:|:.|:..... |.|.....|.|..||           ..|.|
 Frog   320 SEKCDCINAVRCYHINGGCLCEHGFKGEACDERMCPPGLYGMPCNLRCLCDPLHSQSCHPMSGEC 384

  Fly   263 VCKPGY--VMRNDLCQPH------CEK---CSDNAHCVA-PNQCECFPGYESSGADKKCV----- 310
            .||||:  :..|:.| ||      |::   |.:...|.: ..:|.|.||:........|.
 Frog   385 ACKPGWSGLYCNETC-PHGYYGTNCQELCVCLNGGSCDSETGECICAPGFTGPQCSSYCPMETYG 448

  Fly   311 PKCSK--GCTNGFCFAP--ETCVCSIGYQMGPNQVCEPKCSLNCVHG----KCTSPETCTCDPGY 367
            ||||:  ||.|....:|  .:|||..|:|.|       .||:.|..|    .|.  .||.|
 Frog   449 PKCSQKCGCKNSLACSPIDGSCVCKEGWQKG-------DCSVPCPKGTWGYNCN--RTCEC---- 500

  Fly   368 RFKDNSHHECDPI-----CDSGCSNGHCVAPNFCICHDG-------YQL---NSTN--PVTSMC- 414
                |:...|.||     |.||.....|..|    |.||       .|.   ||.|  |:|..|
 Frog   501 ----NNGASCSPISGLCSCTSGWHGDKCEQP----CKDGTFGPGCRQQCECENSDNCDPITGQCW 557

  Fly   415 ------QPICK-GCQFG----------DC-----VAP--NVCECNVGYE--NINGLCELQTTTDS 453
                  .|.|| .|:.|          ||     .:|  ..|.|..|:.  :.:.:|      ..
 Frog   558 CLPGWTGPECKQSCEEGFWGRKCNMTCDCKNGASCSPKDGTCTCAAGFRGPDCDNIC------PH 616

  Fly   454 YEYSTTTVELQSSTVDPQLQTSTSEVPHSNCT---AGCMCWIEYDGMGTFNTAKCAKIC-VDPQD 514
            ..|....|          |....|.  ||.|.   ..|.|:..:.|      ..|::.| :....
 Frog   617 GRYGKKCV----------LTCKCSN--HSTCNHIDGSCKCFPGWKG------NDCSEPCTLGFWG 663

  Fly   515 KPCLNLDNCQ----CDLSSGQLV---------CQEDSDMDYSGENSRYVCHILPEQGARSE---- 562
            |.|.:..|||    |..:.|..:         |.|...:...|||..:.|..  :.||..:
 Frog   664 KDCASTCNCQHGGHCSPTDGTCICPIGWTGKTCSEVCPLGSYGENCIHKCRC--QNGAECDHMTG 726

  Fly   563 ------------AEVRIPDRTGSSNKWMI-----------IVGSC-------------------- 584
                        .|::.||||.......:           :.|||
 Frog   727 KCSCLPGYHGAFCEIKCPDRTYGLKCHQVCECLNNATCHHVTGSCQCEAAWFGVHCEKSLNVEVP 791

  Fly   585 -------------AGMIIGVAA------TIIG-IKYYR 602
                         .|.|||:.|      .:|| ..|||
 Frog   792 FTMVPNTPPATDSIGPIIGIVALAILVVVLIGFFLYYR 829

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
NimC1	NP_001260453.1	None
pear1	XP_017952446.2	EMI	28..98	CDD:462204	22/77 (29%)
		EGF_CA	280..325	CDD:473889	8/44 (18%)
		Laminin_EGF	546..586	CDD:395007	10/39 (26%)