DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment NimC1 and Stab1

DIOPT Version :9

Sequence 1:NP_001260453.1 Gene:NimC1 / 34816 FlyBaseID:FBgn0259896 Length:622 Species:Drosophila melanogaster
Sequence 2:XP_008769275.1 Gene:Stab1 / 100363145 RGDID:2324745 Length:2630 Species:Rattus norvegicus


Alignment Length:406 Identity:104/406 - (25%)
Similarity:147/406 - (36%) Gaps:115/406 - (28%)


- Green bases have known domain annotations that are detailed below.


  Fly    14 SLSFGTSFAILRHGLNDCSHPESVPYNRKVLKSKLVP-FQQYSYFHGWVTK--------YRHQYV 69
            |..||.| .||..|.:.|.|..:     :.|:.|.|. .:::....|:..:        ||....
  Rat  1304 SALFGLS-GILAVGSSRCLHSHA-----EALREKCVNCTRKFRCTQGFQLQDTPRKSCVYRSGLS 1362

  Fly    70 YEDETAY---RTVMRPSCCEGYEGSVENCKPVCRQQCPQHGFCSSPNTCSCNAGYGGIDCHPVCP 131
            :....:|   :.:..|.||.|:.|::  |:|                   |..|.||        
  Rat  1363 FSRGCSYTCAKKIQVPDCCPGFFGTL--CEP-------------------CPGGLGG-------- 1398

  Fly   132 TVCGKNEFC-DR---PGVCSCQNGYKRTSPSDNCL-----PVCEKECG-HHSFCSE----PGKCE 182
             ||..:..| ||   .|.|.||.|:..|: .:.|.     |.|...|. .|..|.|    .|.|.
  Rat  1399 -VCSGHGQCQDRFLGNGECRCQEGFHGTA-CEMCELGRYGPTCSGVCDCDHGLCQEGLRGNGSCI 1461

  Fly   183 CEPGYEKVGNGTVFPDGYKNNSNGNCSPICPKDCGQNSRCVRPG----VCECENGYAGDDGGTNC 243
            |..|::.:.......|..           |||.|..|:.|::..    ||.|..||:|:  |:.|
  Rat  1462 CNVGWQGLRCDQKITDRQ-----------CPKKCDPNANCIQDSAGIPVCVCAAGYSGN--GSYC 1513

  Fly   244 RPV--CST----CPENGLC--LSPG--VCVCKPGYVMRNDLCQP------HCEKCSDNAHCV--A 290
            ..|  |::    |.....|  ::||  .|.|..||....:|||.      |...|..||.|:  .
  Rat  1514 SEVDPCTSGHGGCSPYANCTKVAPGQRTCTCLDGYTGDGELCQEINSCLVHNGGCHVNAECIPTG 1578

  Fly   291 PNQ--CECFPGYESSGADK-KCVPKCSKGCTNGFCFAP-----------ETCVCSIGYQMGPNQV 341
            |.|  |.|..||...|... |.:..||:  .||.| :|           .||.|...:.:|....
  Rat  1579 PQQVSCNCREGYSGDGIQSCKLLDPCSQ--NNGGC-SPYAVCKSTGDGQRTCSCDSTHTVGDGIT 1640

  Fly   342 CEPKCSLNCVHGKCTS 357
            |..:..|..:..|..|
  Rat  1641 CHGRVGLELLRNKYAS 1656

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
NimC1NP_001260453.1 None
Stab1XP_008769275.1 Fasciclin 391..494 CDD:295423
Fasciclin 523..647 CDD:280607
EGF_3 834..863 CDD:289699
EGF_3 918..949 CDD:289699
EGF_3 955..991 CDD:289699
Fasciclin <1100..1180 CDD:280607
Fasciclin 1224..1313 CDD:295423 4/9 (44%)
EGF_3 1519..1555 CDD:289699 9/35 (26%)
EGF_3 1561..1595 CDD:289699 11/33 (33%)
EGF_3 1604..1641 CDD:289699 10/39 (26%)
Fasciclin 1666..1770 CDD:280607
Fasciclin 1796..1926 CDD:280607
EGF_Lam 2037..2082 CDD:238012
EGF_3 2154..2189 CDD:289699
EGF_3 2195..2232 CDD:289699
Link_Domain 2267..2359 CDD:295393
FAS1 2426..2521 CDD:214719
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG1218
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.900

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