DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment NimB5 and SCARF2

DIOPT Version :9

Sequence 1:	NP_001188802.1	Gene:	NimB5 / 34815	FlyBaseID:	FBgn0028936	Length:	315	Species:	Drosophila melanogaster
Sequence 2:	NP_699165.3	Gene:	SCARF2 / 91179	HGNCID:	19869	Length:	871	Species:	Homo sapiens

Alignment Length:	382	Identity:	88/382 - (23%)
Similarity:	110/382 - (28%)	Gaps:	174/382 - (45%)

- Green bases have known domain annotations that are detailed below.

  Fly   100 IWVPPDTVEKYSYPSVIQTDQANRL----SLIEVCCTGY-SASRLMGVTVCRAQCGC-QNGSCKI 158
            :|:.||||.    |..:.....|..    |.:..||.|: ......|:.||.....| :|..|..
Human    34 LWMLPDTVA----PQELNPRGRNVCRAPGSQVPTCCAGWRQQGDECGIAVCEGNSTCSENEVCVR 94

  Fly   159 PGECECYDGF----------------------------------------VRNDNGDCVFACPLG 183
            ||||.|..|:                                        .|.....|..||.
Human    95 PGECRCRHGYFGANCDTKCPRQFWGPDCKELCSCHPHGQCEDVTGQCTCHARRWGARCEHACQ-- 157

  Fly   184 CQNGQCY-LDGSCQCDPGY---------KLDETRRFCRP-----ICSSG-----------CGSSP 222
            ||:|.|: ..|:|:|:||:         ....|.| |.|     :|.:|           |.|||
Human   158 CQHGTCHPRSGACRCEPGWWGAQCASACYCSATSR-CDPQTGACLCHAGWWGRSCNNQCACNSSP 221

  Fly   223 ------RHNCTE-------PEICGCSKGYQLTDDG---CQP-----VCEPDC-----GIG----- 256
                  |..|.|       ...|.|.:|.....||   |:|     .|...|     |:|
Human   222 CEQQSGRCQCRERTFGARCDRYCQCFRGRCHPVDGTCACEPGYRGKYCREPCPAGFYGLGCRRRC 286

  Fly   257 GLCKDNNQC--------DCAPGYN-----------------------LRDG-----------VCQ 279
            |.||....|        .|.||:|                       .|||           .|.
Human   287 GQCKGQQPCTVAEGRCLTCEPGWNGTKCDQPCATGFYGEGCSHRCPPCRDGHACNHVTGKCTRCN 351

  Fly   280 AD-----CYQKCNNG--------VCV---------SRNRCLCDPGYTYHEQSTMCVP 314
            |.     |..||:||        ||.         ...||||.||......:..|.|
Human   352 AGWIGDRCETKCSNGTYGEDCAFVCADCGSGHCDFQSGRCLCSPGVHGPHCNVTCPP 408

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID
NimB5	NP_001188802.1	None
SCARF2	NP_699165.3	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..20
		PHA03247	<534..871	CDD:223021
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	570..871
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1218
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900