DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment NimB5 and pear1

DIOPT Version :9

Sequence 1:	NP_001188802.1	Gene:	NimB5 / 34815	FlyBaseID:	FBgn0028936	Length:	315	Species:	Drosophila melanogaster
Sequence 2:	XP_700533.4	Gene:	pear1 / 571812	ZFINID:	ZDB-GENE-091230-1	Length:	1020	Species:	Danio rerio

Alignment Length:	252	Identity:	78/252 - (30%)
Similarity:	101/252 - (40%)	Gaps:	64/252 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly   109 KYSYPSVIQTDQANRLSLIEVCCTGYSASRLMGVTVCRAQCGCQNGSCKIPGECECYDGFVRNDN 173
            |..|..|::.|...|..    ||.|:..||...|..|..:  |.:|.|..|..|:|..|: |.|
Zfish    74 KTLYRQVVKMDYRRRYQ----CCPGFYESRNKCVPRCTKE--CVHGRCVAPDRCQCEMGW-RGD- 130

  Fly   174 GDCVFACP-----------LGCQN-GQC-YLDGSCQCDPGYKLDETRRFCRPIC----------- 214
             ||..:|.           ..||| |:| .|.|:|||..||    |.:.|...|
Zfish   131 -DCSSSCDGQHWGPGCRRLCECQNGGECDVLTGNCQCPAGY----TGQHCHDPCPVKWFGQGCRQ 190

  Fly   215 SSGCGSSPRHNCTEPEICGCSKGYQLTDDGCQPVC-EP-------DCGIGGLCKDNNQCDCAPGY 271
            ...||:....|.|..| |.|.:|:  |...|:..| .|       .|..||:|:.|..|.|.||:
Zfish   191 ECQCGTGGICNQTTGE-CVCKQGF--TGTLCEESCPRPKRCAARCPCQNGGICQGNGVCLCPPGW 252

  Fly   272 ----------NLRDGV-CQADCYQKCNN-GVC-VSRNRCLCDPGYTYHEQSTMCVPV 315
                      ..|.|: |..||.  |:| |.| ..:.:|.||.|||....:..| ||
Zfish   253 MGPVCTERCPPGRFGINCSKDCL--CHNGGHCDQEKGQCQCDAGYTGERCNEEC-PV 306

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
NimB5	NP_001188802.1	None
pear1	XP_700533.4	EMI	29..96	CDD:284877	8/25 (32%)
pear1	XP_700533.4	Laminin_EGF	411..451	CDD:278482
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1218
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900