Protein Alignment NimB5 and DKK3

DIOPT Version :10

• Sequence 1: NP_609692.3
• Gene: NimB5 / 34815
• FlyBaseID: FBgn0028936
• Length: 315
• Species: Drosophila melanogaster
• Sequence 2: NP_001317149.1
• Gene: DKK3 / 27122
• HGNCID: 2893
• Length: 364
• Species: Homo sapiens
• Alignment Length: 310
• Identity: 65/310 - (20%)
• Similarity: 91/310 - (29%)
• Gaps: 98/310 - (31%)

  Fly    61 RPGPANFQDPRNVELQPKRREYLIRSHETQSDRGQHKCRIWVPPDTVEKYSYPSVIQTDQANRLS 125
            :||||.........|....||.    .|...|. |||.|     ..||:      ::.::|...:
Human    33 KPGPALSYPQEEATLNEMFREV----EELMEDT-QHKLR-----SAVEE------MEAEEAAAKA 81

  Fly   126 LIEVCCTGYSASRLMGVTVCRAQCGCQNGSCKIPGECECYDGFVRNDNGDCVFA----CPLGCQN 186
            ..||.......| ....|....:.|  |.:..:..|..   ....|..|..||:    ..:|.:.
Human    82 SSEVNLANLPPS-YHNETNTDTKVG--NNTIHVHREIH---KITNNQTGQMVFSETVITSVGDEE 140

  Fly   187 G----QCYLDGSCQCDPGYKLDETRRFCRPICSSGCGSSPRHNCT-EPEICG--------CSKGY 238
            |    :|.:|..|......:....:..|:|     | ...|..|| :.|.||        |:|..
Human   141 GRRSHECIIDEDCGPSMYCQFASFQYTCQP-----C-RGQRMLCTRDSECCGDQLCVWGHCTKMA 199

  Fly   239 QLTDDG--------CQ-------------PVCEPDCGIGGLCKDN------------------NQ 264
            ....:|        ||             |||.|....|.||.|.                  ::
Human   200 TRGSNGTICDNQRDCQPGLCCAFQRGLLFPVCTPLPVEGELCHDPASRLLDLITWELEPDGALDR 264

  Fly   265 CDCAPGYNLRDGVCQADCYQKCNNGVCVSRNRCLCDPGYTYHEQSTMCVP 314
            |.||.|.     :||.....:...|..         |....|....:|.|
Human   265 CPCASGL-----LCQPHRLPRLEPGFV---------PSLPSHSLVYVCKP 300

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
NimB5	NP_609692.3	None
DKK3	NP_001317149.1	Dkk3_N_Cys1	41..196	CDD:438008	37/182 (20%)
		Dkk3_Cys2	199..278	CDD:438000	17/83 (20%)