Protein Alignment NimB5 and DKK4

DIOPT Version :10

• Sequence 1: NP_609692.3
• Gene: NimB5 / 34815
• FlyBaseID: FBgn0028936
• Length: 315
• Species: Drosophila melanogaster
• Sequence 2: NP_055235.1
• Gene: DKK4 / 27121
• HGNCID: 2894
• Length: 224
• Species: Homo sapiens
• Alignment Length: 192
• Identity: 42/192 - (21%)
• Similarity: 53/192 - (27%)
• Gaps: 82/192 - (42%)

  Fly   183 GCQNG-QCYLDGSCQCDPGYKLDETRRFC------RPICSSGCGSSPRHNCTEPEICGCSKGYQL 240
            |.:.| ||..|..|         .||:||      :|.|::..|.  |..|....:| | .|...
Human    34 GARKGSQCLSDTDC---------NTRKFCLQPRDEKPFCATCRGL--RRRCQRDAMC-C-PGTLC 85

  Fly   241 TDDGC---------------------------------QPVCEPDC--GIGGLCKDNNQC----D 266
            .:|.|                                 ||..:|..  ..|...::...|    |
Human    86 VNDVCTTMEDATPILERQLDEQDGTHAEGTTGHPVQENQPKRKPSIKKSQGRKGQEGESCLRTFD 150

  Fly   267 CAPGYNLRDGVCQADCYQK-C-----NNGVCVSR------------NRCLCDPGYTYHEQST 310
            |.||.     .|....:.| |     ...||..|            .||.|.||.....|.|
Human   151 CGPGL-----CCARHFWTKICKPVLLEGQVCSRRGHKDTAQAPEIFQRCDCGPGLLCRSQLT 207

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
NimB5	NP_609692.3	None
DKK4	NP_055235.1	Dkk4_Cys1	37..91	CDD:438007	18/66 (27%)
		DKK-type Cys-1	41..90		16/61 (26%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	109..139		4/29 (14%)
		Dkk4_Cys2	128..221	CDD:438001	20/85 (24%)
		DKK-type Cys-2	145..218		18/68 (26%)