DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment NimB5 and Dkk4

DIOPT Version :9

Sequence 1:	NP_001188802.1	Gene:	NimB5 / 34815	FlyBaseID:	FBgn0028936	Length:	315	Species:	Drosophila melanogaster
Sequence 2:	NP_663567.1	Gene:	Dkk4 / 234130	MGIID:	2385299	Length:	221	Species:	Mus musculus

Alignment Length:	175	Identity:	38/175 - (21%)
Similarity:	58/175 - (33%)	Gaps:	49/175 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly   131 CTGYSASRLMGVTVCRAQCGCQNGSCKIPGE------CECYDG----FVRNDNGDCVFACPLGCQ 185
            |..:...|....|..|.:..||..:...||.      |...:.    ..||.:|          |
Mouse    53 CLAFHDERSFCATCRRVRRRCQRSAVCCPGTVCVNDVCTAVEDTRPVMDRNTDG----------Q 107

  Fly   186 NGQCYLDGSCQCDPGYKLDETRRFCRPICSSGCGSSPR--HNCTEPEICG----CSKGYQLTDDG 244
            :| .|.:|:.:    :..:|.|...:|.......|..:  .:|.....||    |::.:
Mouse   108 DG-AYAEGTTK----WPAEENRPQGKPSTKKSQSSKGQEGESCLRTSDCGPGLCCARHF------ 161

  Fly   245 CQPVCEPDCGIGGLC-----KDNNQ-------CDCAPGYNLRDGV 277
            ...:|:|....|.:|     ||..|       |||.||...|..|
Mouse   162 WTKICKPVLREGQVCSRRGHKDTAQAPEIFQRCDCGPGLTCRSQV 206

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
NimB5	NP_001188802.1	None
Dkk4	NP_663567.1	Dickkopf_N	41..91	CDD:368068	8/37 (22%)
		DKK-type Cys-1	41..90		8/36 (22%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	101..143		11/56 (20%)
		DKK-type Cys-2	145..218		18/68 (26%)
		Prokineticin	<145..202	CDD:148298	16/62 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1218
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900