Protein Alignment NimB5 and VWDE

DIOPT Version :10

• Sequence 1: NP_609692.3
• Gene: NimB5 / 34815
• FlyBaseID: FBgn0028936
• Length: 315
• Species: Drosophila melanogaster
• Sequence 2: NP_001129396.1
• Gene: VWDE / 221806
• HGNCID: 21897
• Length: 1590
• Species: Homo sapiens
• Alignment Length: 353
• Identity: 89/353 - (25%)
• Similarity: 126/353 - (35%)
• Gaps: 103/353 - (29%)

  Fly    14 HLMVCLPSIYTNVPSYSDRYNRRPVS---QDP-GMGTYGRGYMENRQLSYNRPGPANFQDPRNVE 74
            :|.||||..:.::....       :|   .:| |:|:|..|:.     ||:...|...:    ||
Human  1202 YLCVCLPGFHGSLCEVD-------ISGCQSNPCGLGSYISGFH-----SYSCDCPPELK----VE 1250

  Fly    75 LQ-----PKRREYLIRS----HETQSDRGQHKCRIWVPPD-----TVEKYS--------YPSVIQ 117
            .|     ..:...|.||    ::.:.|:.....:..|.|.     |:.||.        .|::.:
Human  1251 TQFVNQFTTQTVVLTRSDKSVNKEEDDKNAQGRKRHVKPTSGNAFTICKYPCGKSRECVAPNICK 1315

  Fly   118 TDQANRLSLIEVCCTGYSASRLMGVTVCRAQCGCQNGSCKIPGECECYDGF------------VR 170
                        |..||..|... ..:|...|. .:|.|..|..|:|..|.            ..
Human  1316 ------------CKPGYIGSNCQ-TALCDPDCK-NHGKCIKPNICQCLPGHGGATCDEEHCNPPC 1366

  Fly   171 NDNGDC----VFACPLG--------------CQN-GQCYLDGSCQCDPG-YKLDETRRFCRPICS 215
            ...|.|    :..||.|              |:| |||.....|||.|| |....:...|.|:|.
Human  1367 QHGGTCLAGNLCTCPYGFVGPRCETMVCNRHCENGGQCLTPDICQCKPGWYGPTCSTALCDPVCL 1431

  Fly   216 SGCGSSPRHNCTEPEICGCSKGYQLTDDGCQ-PVCEPDCGIGGLCKDNNQCDCAPGY---NLRDG 276
            :| ||     |.:|..|.|..|:  ..:.|| ..|.|.|..||.|..||.|.|..||   ..:..
Human  1432 NG-GS-----CNKPNTCLCPNGF--FGEHCQNAFCHPPCKNGGHCMRNNVCVCREGYTGRRFQKS 1488

  Fly   277 VCQADCYQKCNNGVCVSRNRCLCDPGYT 304
            :|...|   .|.|.||..:.|.|..|::
Human  1489 ICDPTC---MNGGKCVGPSTCSCPSGWS 1513

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
NimB5	NP_609692.3	None
VWDE	NP_001129396.1	VWD	423..581	CDD:214566
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1268..1288		1/19 (5%)