DRSC/TRiP Functional Genomics Resources

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Protein Alignment NimB5 and MEGF6

DIOPT Version :9

Sequence 1:NP_001188802.1 Gene:NimB5 / 34815 FlyBaseID:FBgn0028936 Length:315 Species:Drosophila melanogaster
Sequence 2:XP_011539187.1 Gene:MEGF6 / 1953 HGNCID:3232 Length:1603 Species:Homo sapiens


Alignment Length:324 Identity:82/324 - (25%)
Similarity:114/324 - (35%) Gaps:91/324 - (28%)


- Green bases have known domain annotations that are detailed below.


  Fly    64 PANFQDPRNVELQPKRREYLIRSHETQSDRGQHKCRIWVPPDTVEKYSYPSVIQTDQANRLSLIE 128
            |..||.|        |.:|.:....|.:...||:| :..|...:.:......:.||....|: |.
Human   212 PPGFQGP--------RCQYDVDECRTHNGGCQHRC-VNTPGSYLCECKPGFRLHTDSRTCLA-IN 266

  Fly   129 VCCTGYSASR--LMGVTVCRAQCGC---------------------QNGSCK-----IPG--ECE 163
            .|..|....:  .:.:|:.|.:|.|                     :||||.     :.|  .||
Human   267 SCALGNGGCQHHCVQLTITRHRCQCRPGFQLQEDGRHCVRRSPCANRNGSCMHRCQVVRGLARCE 331

  Fly   164 CY-------DGFVRNDNGDC---VFACPLGCQNGQCYLDGS--CQCDPGYKLDETRRFCRPI--- 213
            |:       ||....|..:|   :..|..||.|.|    ||  |.|..||:|....|.|..|   
Human   332 CHVGYQLAADGKACEDVDECAAGLAQCAHGCLNTQ----GSFKCVCHAGYELGADGRQCYRIEME 392

  Fly   214 -----------CSSGCGSSPRHNCTEPEICGCSKGYQLTDDGCQPVCEPDCGIGGLCKD---NN- 263
                       ||.||.    |....| :|.|.:||:|..|....:...||.....|:.   || 
Human   393 IVNSCEANNGGCSHGCS----HTSAGP-LCTCPRGYELDTDQRTCIDVDDCADSPCCQQVCTNNP 452

  Fly   264 ---QCDCAPGYNLRDGVCQADCYQKC--NNGVC-------VSRNRCLCDPGYTYHEQSTMCVPV 315
               :|.|..||.|....|..:...:|  :.|.|       ....:|.|:.||..||....|.|:
Human   453 GGYECGCYAGYRLSADGCGCEDVDECASSRGGCEHHCTNLAGSFQCSCEAGYRLHEDRRGCSPL 516

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
NimB5NP_001188802.1 None
MEGF6XP_011539187.1 EMI 108..176 CDD:284877
vWFA <215..261 CDD:294047 12/54 (22%)
FXa_inhibition 268..304 CDD:291342 6/35 (17%)
vWFA <342..384 CDD:294047 15/45 (33%)
FXa_inhibition 397..432 CDD:291342 12/39 (31%)
vWFA <432..469 CDD:294047 10/36 (28%)
vWFA <472..511 CDD:294047 9/38 (24%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG1218
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.900

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