Protein Alignment NimB4 and MEGF11

DIOPT Version :10

• Sequence 1: NP_788046.1
• Gene: NimB4 / 34814
• FlyBaseID: FBgn0028542
• Length: 448
• Species: Drosophila melanogaster
• Sequence 2: NP_001371957.1
• Gene: MEGF11 / 84465
• HGNCID: 29635
• Length: 1140
• Species: Homo sapiens
• Alignment Length: 440
• Identity: 105/440 - (23%)
• Similarity: 140/440 - (31%)
• Gaps: 159/440 - (36%)

  Fly    95 EVPAVFFQYDKEVKIVGNSSTNPYMNVIEVCC---------------------KGWRRYEYDWSQ 138
            |.|.|...::.....|..|..:|:..:....|                     :|.|......||
Human    23 EDPNVCSHWESYAVTVQESYAHPFDQIYYTRCTDILNWFKCTRHRISYKTAYRRGLRTMYRRRSQ 87

  Fly   139 CVPDCGERCQENGFCVAGGKCVCFTDFVLNYRNNCVPTCPLGCPHGRCYLNGTCQCDKGYELDGS 203
            |.|         |:..:|       ||       |:|.|...|.||||....||.|:.|:.....
Human    88 CCP---------GYYESG-------DF-------CIPLCTEECVHGRCVSPDTCHCEPGWGGPDC 129

  Fly   204 RKFCQ-----PQCNATCG-HNEVCLEP--GKCSCAEGYTRGLRESAALGCQPICIP--------- 251
            ...|.     |.|:..|. .|.....|  |.|.||.|: ||.|      |:.:|.|
Human   130 SSGCDSDHWGPHCSNRCQCQNGALCNPITGACVCAAGF-RGWR------CEELCAPGTHGKGCQL 187

  Fly   252 --DCGYGHCVRP--NECECFPGFQKRKNGITCEGDC-----------YMTCENGFCANKTT--CV 299
              .|.:|....|  .||.|.||:    .|:.||..|           ...|:||...:..|  |.
Human   188 PCQCRHGASCDPRAGECLCAPGY----TGVYCEELCPPGSHGAHCELRCPCQNGGTCHHITGECA 248

  Fly   300 CQNGY------------RYDKNTTTCLPDC----GDNCDNGVCISPGNCRCFKGYVRNRERCEAV 348
            |..|:            .:.:|   |..||    |..||:    ..|.|.|..||:  .:||:..
Human   249 CPPGWTGAVCAQPCPPGTFGQN---CSQDCPCHHGGQCDH----VTGQCHCTAGYM--GDRCQEE 304

  Fly   349 C-VGGCGFY----------GKCIAPNVCGCAIVP---GPERTYQRCEYGL----------CNA-- 387
            | .|..||.          |:| :|....|...|   ||....:.|..||          |:|
Human   305 CPFGSFGFQCSQHCDCHNGGQC-SPTTGACECEPGYKGPRCQERLCPEGLHGPGCTLPCPCDADN 368

  Fly   388 -------MGRCRCQVGMT-----------RFIDRCMSPDTVTTYASMNPV 419
                   .|.|.||.|.:           .:.|.|..|.|....|..:.:
Human   369 TISCHPVTGACTCQPGWSGHHCNESCPVGYYGDGCQLPCTCQNGADCHSI 418

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
NimB4	NP_788046.1	None
MEGF11	NP_001371957.1	EMI	25..94	CDD:462204	13/77 (17%)
		EGF_CA	275..320	CDD:473889	15/50 (30%)
		EGF_CA	362..409	CDD:473889	10/46 (22%)