DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment NimB4 and megf6b

DIOPT Version :9

Sequence 1:	NP_788046.1	Gene:	NimB4 / 34814	FlyBaseID:	FBgn0028542	Length:	448	Species:	Drosophila melanogaster
Sequence 2:	XP_009304569.1	Gene:	megf6b / 557764	ZFINID:	ZDB-GENE-101112-3	Length:	1589	Species:	Danio rerio

Alignment Length:	423	Identity:	111/423 - (26%)
Similarity:	143/423 - (33%)	Gaps:	161/423 - (38%)

- Green bases have known domain annotations that are detailed below.

  Fly    91 KCRQEVPAVFFQYDKEVKIV--GNSSTNPYMNVIEVCCKGWRRYEYDWSQCVPDCGERCQENGF- 152
            :|.|..||.:|........|  .|||.:......| |..||..         ..|.:||....|
Zfish  1014 RCNQTCPAGWFGVSCSQTCVCHNNSSCDAVSGQCE-CGAGWTG---------DTCSQRCPAGVFG 1068

  Fly   153 --CVAGGKCVCFTDFVLNYRN--NCVP--------------TCPLGCPHGR----CYLNGTCQCD 195
              ||  .:|:|        :|  :|.|              .|.|.||.||    |  ...|:|.
Zfish  1069 DGCV--HRCLC--------QNGASCDPESGHCFCPSGWTGAACQLECPAGRFGSDC--QDRCECV 1121

  Fly   196 KGYELDG--SRKFCQP---------QC-----------NATCGHNEVCLE-PGKCSCAEGYTRGL 237
            .|.:.||  .|..|.|         :|           ...|.|..||.. .|:|.|..|: ||.
Zfish  1122 NGAQCDGQTGRCVCPPGWTGERCENECERGWFGVGCEDRCQCDHGAVCHHVSGQCLCPAGW-RGR 1185

  Fly   238 RESAALGCQPICIP-----DCGYGHCVRPN---------ECECFPGFQKRKNGITCE-------- 280
            |      |:..|:|     || ...|..|:         .|.|.|||    .|..||
Zfish  1186 R------CEKACLPGSFGQDC-VQRCSCPSGSSCHHVTGHCGCAPGF----TGDGCEHSCLPGTF 1239

  Fly   281 -GDCYMTCE----NGFCANKT-TCVCQNGYRYDKNTTTCLPD------CGDNCD---NGVCIS-P 329
             .||...|:    |..|...| .|.|..|:...|...|| |.      |...|:   .|||:| .
Zfish  1240 GQDCNQVCQCSERNQLCHPVTGVCYCAPGFTGLKCEQTC-PQGLYGSGCEHQCECLNGGVCLSDS 1303

  Fly   330 GNCRCFKGYVRNRERCEAVC-----------VGGCG-------FYGKCIAPNVC-------GCAI 369
            |:|:|..|::  ..:|...|           |..||       ..|:|.|..||       ||:
Zfish  1304 GSCQCPAGFI--GAQCNQTCPAGRYGLDCAHVSACGTGVRNDPATGRCTAHQVCPPGWFGSGCS- 1365

  Fly   370 VPGPERTYQRCE---YGLCNAM-GRCRCQVGMT 398
                    |||:   .|:|:.: |.|.|.:|.|
Zfish  1366 --------QRCDCSNRGVCDGVSGNCSCALGWT 1390

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID
NimB4	NP_788046.1	None
megf6b	XP_009304569.1	EMI	33..102	CDD:284877
		FXa_inhibition	152..187	CDD:291342
		vWFA	<184..227	CDD:294047
		FXa_inhibition	234..270	CDD:291342
		FXa_inhibition	276..311	CDD:291342
		vWFA	<308..350	CDD:294047
		FXa_inhibition	363..398	CDD:291342
		vWFA	<396..436	CDD:294047
		FXa_inhibition	445..480	CDD:291342
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1218
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900