DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment NimB4 and Stab2

DIOPT Version :9

Sequence 1:NP_788046.1 Gene:NimB4 / 34814 FlyBaseID:FBgn0028542 Length:448 Species:Drosophila melanogaster
Sequence 2:XP_038934441.1 Gene:Stab2 / 282580 RGDID:628822 Length:2569 Species:Rattus norvegicus


Alignment Length:471 Identity:114/471 - (24%)
Similarity:158/471 - (33%) Gaps:148/471 - (31%)


- Green bases have known domain annotations that are detailed below.


  Fly    21 VLHGLELQLHEQQLQQQKDEQLRLRAE----QRQRELLREHEALQRRLSSSTTTRKPYIIPNGLS 81
            |:||||..|..|:.:...::.:.:|.|    .:|.....|.:.|:.       ||          
  Rat  1261 VIHGLEKVLEIQKNRCDNNDTIIVRGECGKCSQQAPCPLETKPLRE-------TR---------- 1308

  Fly    82 LPRRGEHPDKCRQEVPAVFFQYDKEVKIVGNSSTNPYMNVIEVCCKGWRRYEYDWSQC--VPDCG 144
                     ||   :.:::|...:.| .:|.........:...||.|     :...||  .|..|
  Rat  1309 ---------KC---IYSIYFMGKRSV-FIGCQPQCVRTIITRACCAG-----FFGPQCQACPGRG 1355

  Fly   145 ER-CQENGFCVAG----GKCVCFTDFVLNYRNNCVPTCPLG-----------CPHGRCYL----N 189
            :. |..||||:.|    |.|.|    .|.:......||..|           |.||||..    :
  Rat  1356 QNVCSGNGFCLDGVNGTGTCQC----GLGFSGTACETCTEGKYGIHCDQACSCVHGRCSQGPLGD 1416

  Fly   190 GTCQCDKGYE-LDGSRKFCQPQCNATCGHNEVC-LEP-GK--CSCAEGYTRGLRESAALGCQPIC 249
            |:|.||.|:. :....:.....||.||..:..| |:| ||  |.||.|:.               
  Rat  1417 GSCDCDVGWRGVKCDMEITTDNCNGTCHTSANCLLDPDGKASCKCAAGFR--------------- 1466

  Fly   250 IPDCGYGH-CVRPNECECFPGFQKRKNGITCEGDCYMTCENGFCANKTTCVCQNGYRYD----KN 309
                |.|. |...|.||...|      |.:.:.||..|     ......|||:.||..|    ..
  Rat  1467 ----GNGTVCTAINACETSNG------GCSTKADCKRT-----TPGNRVCVCKAGYTGDGIVCLE 1516

  Fly   310 TTTCLPDCGDNCD-NGVCISPGN----CRCFKGYVRNRERCEA--VCV---GGCGFYGKC----I 360
            ...||.:.| .|| |..|...|.    |.|...|..:.:.|..  ||:   |||..:..|    .
  Rat  1517 INPCLENHG-GCDRNAECTQTGPNQAVCNCLPKYTGDGKVCSLINVCLTNNGGCSPFAFCNYTEQ 1580

  Fly   361 APNVCGCAIVPGPERTYQRCEYGLCNAMGRCRCQVGMTRFIDRCMSPDT-----------VTTYA 414
            ...:|.|.    |:.|..    |:.     ||..:    :.:...:|.|           |...|
  Rat  1581 DQRICTCK----PDYTGD----GIV-----CRGSI----YGELPKNPSTSQYFFQLQEHAVRELA 1628

  Fly   415 SMNPVKVNASLIQEFN 430
            ...|..|.|.|...||
  Rat  1629 GPGPFTVFAPLSSSFN 1644

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
NimB4NP_788046.1 None
Stab2XP_038934441.1 EGF_CA 254..283 CDD:419698
EGF_3 334..369 CDD:403986
Fasciclin 390..512 CDD:396845
Fasciclin 533..658 CDD:396845
EGF_3 840..868 CDD:403986
EGF_3 881..912 CDD:403986
EGF_3 923..955 CDD:403986
EGF_3 961..997 CDD:403986
Fasciclin 1014..1133 CDD:396845
Fasciclin 1152..1269 CDD:396845 5/7 (71%)
EGF_3 1478..1514 CDD:403986 13/46 (28%)
EGF_3 1520..1556 CDD:403986 11/36 (31%)
EGF_3 1562..1598 CDD:403986 10/48 (21%)
Fasciclin 1629..1729 CDD:396845 6/16 (38%)
Fasciclin 1754..1885 CDD:396845
EGF_CA 2059..2084 CDD:419698
EGF_3 2090..2125 CDD:403986
EGF_3 2131..2168 CDD:403986
Link_Domain 2202..2294 CDD:413401
FAS1 2360..2449 CDD:214719
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG1218
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.900

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