DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment NimB4 and Stab2

DIOPT Version :9

Sequence 1:NP_788046.1 Gene:NimB4 / 34814 FlyBaseID:FBgn0028542 Length:448 Species:Drosophila melanogaster
Sequence 2:NP_619614.1 Gene:Stab2 / 192188 MGIID:2178743 Length:2559 Species:Mus musculus


Alignment Length:347 Identity:87/347 - (25%)
Similarity:118/347 - (34%) Gaps:124/347 - (35%)


- Green bases have known domain annotations that are detailed below.


  Fly   121 VIEV--CCKGWRRYEYDWSQCVPDC-------GERCQENGFCV----AGGKCVCFTDFVLNYRNN 172
            |:.|  ||.|:         .:|||       ...|...|.|.    ..|:|.|.|.|.......
Mouse  1952 VVHVPRCCSGY---------FMPDCQACPGGPDTPCNNRGMCYDQYKPTGQCQCHTGFNGTACEL 2007

  Fly   173 CV-----PTC-PLGC-PHGRCYLNGTCQCDKGYELDGSRKFCQPQCNATCGHNEVCLEPGKCSCA 230
            |:     |.| |.|| .||        |||:|  :.||                     |:|.|.
Mouse  2008 CLPGRFGPDCQPCGCSEHG--------QCDEG--ITGS---------------------GQCLCE 2041

  Fly   231 EGYTRGLRESAALGCQPICIPDCG-YGHCVRPNECECFPGFQKRKNGITCEGDCYMTCENGFCA- 293
            .|:| |....|.....|:|||.|. :..|:..|.|.|...::  .:||||....:....||.|| 
Mouse  2042 AGWT-GRFCDAPTVVIPVCIPACSMHATCMENNTCVCNLNYE--GDGITCTVVDFCKQNNGGCAK 2103

  Fly   294 --------NKTTCVCQNGYRYDKNTTTCLPDCGDNCDNGVC--------ISPG--NCRCFKGYVR 340
                    .:.:|.||.||:.|.::.|.:..|. |..||.|        ..||  .|.|...||.
Mouse  2104 VAKCSQKGTQVSCSCQKGYKGDGHSCTEIDPCA-NGVNGGCHEHATCRMTGPGKQKCECKSHYVG 2167

  Fly   341 NRERCEAV------CV---GGCGFYGKCI---------------------------APNVC---G 366
            :...||..      |:   |.|.....|:                           |...|   .
Mouse  2168 DGRDCEPEQLPLDRCLQDNGQCHPDANCVDLHFQDTTVGVFHLRSPLGQYKLTFDKAKEACAKEA 2232

  Fly   367 CAIVPGPERTY-QRCEYGLCNA 387
            .:|....:.:| |:.:|.||:|
Mouse  2233 ASIATYNQLSYAQKAKYHLCSA 2254

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
NimB4NP_788046.1 None
Stab2NP_619614.1 EGF_3 254..283 CDD:289699
EGF_3 334..369 CDD:289699
Fasciclin 390..512 CDD:280607
Fasciclin 533..661 CDD:280607
EGF_3 844..872 CDD:289699
EGF_3 928..959 CDD:289699
EGF_3 965..1001 CDD:289699
Fasciclin 1018..1137 CDD:280607
Fasciclin 1156..1273 CDD:280607
EGF_3 1482..1518 CDD:289699
EGF_3 1524..1560 CDD:289699
EGF_3 1566..1602 CDD:289699
Fasciclin 1628..1733 CDD:280607
Fasciclin 1758..1889 CDD:280607
EGF_3 2094..2129 CDD:289699 10/34 (29%)
EGF_3 2135..2172 CDD:289699 11/37 (30%)
Link_Domain 2206..2297 CDD:295393 9/49 (18%)
FAS1 2363..2452 CDD:214719
Interaction with TMSB4X. /evidence=ECO:0000250 2510..2520
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 2514..2559
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG1218
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.900

Return to query results.
Submit another query.