DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment NimB4 and Tnc

DIOPT Version :9

Sequence 1:	NP_788046.1	Gene:	NimB4 / 34814	FlyBaseID:	FBgn0028542	Length:	448	Species:	Drosophila melanogaster
Sequence 2:	XP_008761976.1	Gene:	Tnc / 116640	RGDID:	621057	Length:	2202	Species:	Rattus norvegicus

Alignment Length:	378	Identity:	96/378 - (25%)
Similarity:	139/378 - (36%)	Gaps:	122/378 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly   119 MNVIEVCCKGWRRYEYDWSQCVPDCGERCQENGFCVAGGKCVCFTDFV------------LNYRN 171
            :|.:.||.:|:...:.....|...|.|   |:|.|| .|:|||...|.            .|.|.
  Rat   232 VNGVCVCFEGYAGLDCGLEVCPVPCSE---EHGMCV-DGRCVCKDGFAGEDCNEPLCFNNCNNRG 292

  Fly   172 NCVPT-----------------CPLGC-PHGRCYLNGTCQCDKGY------------------EL 200
            .||..                 ||..| ..||| :||||.|::|:                  :.
  Rat   293 RCVENECVCDEGFTGEDCSELICPNDCFDRGRC-INGTCYCEEGFTGEDCGELTCPNNCQGHGQC 356

  Fly   201 DGSRKFC----------QPQCNATCGHNEVCLEPGKCSCAEGYTRGLRESAALGCQPICIPDCGY 255
            :..:..|          :.:|.|.|.|:..||. |:|.|.:|:|..  :...|.|...|   .|:
  Rat   357 EEGQCVCNEGFAGADCSEKRCPADCHHHGRCLN-GQCECDDGFTGA--DCGELQCPNGC---SGH 415

  Fly   256 GHCVRPNECECFPGF------QKRKNGITCEGDCYMTCENGFCANKTTCVCQNGYR-YDKNTTTC 313
            |.||. .:|.|..|:      |:|     |..||:   ..|.|. :..|:|:.|:: :|.:..:|
  Rat   416 GRCVN-GQCVCDEGYTGEDCSQRR-----CPNDCH---NRGHCV-QGKCICEQGFKGFDCSEMSC 470

  Fly   314 LPDCGDN--CDNGVCIS-------------------------PGNCRCFKGYVRNRERCEAVCVG 351
            ..||..:  |.||:||.                         .|.|.|..|:. ..:..|..|.|
  Rat   471 PNDCHQHGRCVNGMCICDDDYTGEDCRDRRCPRDCSQRGRCVDGQCICEDGFT-GSDCAELSCPG 534

  Fly   352 GCGFYGKCIAPNVCGC-AIVPGPERTYQRCEYGLCNAMGRCR-----CQVGMT 398
            .|..:|:|: ...|.| ....|.:...|||... |:..|||.     |..|.|
  Rat   535 DCHGHGRCV-NGQCICHEGFTGKDCKEQRCPSD-CHGQGRCEDGQCICHEGFT 585

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
NimB4	NP_788046.1	None
Tnc	XP_008761976.1	EGF_2	346..372	CDD:285248	1/25 (4%)
		EGF_2	377..403	CDD:285248	11/28 (39%)
		EGF_2	408..434	CDD:285248	9/29 (31%)
		EGF_2	434..465	CDD:285248	10/39 (26%)
		EGF_2	468..496	CDD:285248	8/27 (30%)
		EGF_2	504..527	CDD:285248	4/23 (17%)
		EGF_2	533..558	CDD:285248	7/25 (28%)
		EGF_2	592..620	CDD:285248
		FN3	624..710	CDD:238020
		fn3	713..793	CDD:278470
		FN3	804..891	CDD:238020
		fn3	894..976	CDD:278470
		fn3	986..1064	CDD:278470
		fn3	1075..1154	CDD:278470
		fn3	1166..1241	CDD:278470
		fn3	1257..1336	CDD:278470
		fn3	1348..1417	CDD:278470
		fn3	1444..1509	CDD:278470
		fn3	1534..1606	CDD:278470
		fn3	1622..1702	CDD:278470
		FN3	1712..1798	CDD:238020
		fn3	1801..1874	CDD:278470
		fn3	1889..1961	CDD:278470
		Fibrinogen_C	1981..2190	CDD:278572
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910