DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment NimB4 and Stab1

DIOPT Version :9

Sequence 1:	NP_788046.1	Gene:	NimB4 / 34814	FlyBaseID:	FBgn0028542	Length:	448	Species:	Drosophila melanogaster
Sequence 2:	XP_008769275.1	Gene:	Stab1 / 100363145	RGDID:	2324745	Length:	2630	Species:	Rattus norvegicus

Alignment Length:	299	Identity:	78/299 - (26%)
Similarity:	102/299 - (34%)	Gaps:	98/299 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly   125 CCKGWRRYEYDWSQCVPDCGERCQENGFCVAG----GKCVCFTDF------VLNYRN----NCVP 175
            ||||:  :..|.:||.......|...|.|..|    |.|:||.|:      :.:..|    .|..
  Rat   724 CCKGF--FGPDCTQCPGGFSNPCYGKGNCSDGVQGNGACLCFPDYKGIACHICSNPNKHGEQCQE 786

  Fly   176 TCPLGCPHGRC----YLNGTCQ---CDKGYELDGSRKFCQPQCNATCGHNEVCLEPGKCSCAEGY 233
            .|  ||.||.|    ...|.||   |..|::    .:||          ||   ..|.|
  Rat   787 DC--GCVHGLCDNRPGSGGVCQQGTCAPGFQ----GRFC----------NE---SMGNC------ 826

  Fly   234 TRGLRESAALGCQPICIPDCGYGHCVRPN---ECECFPGFQKRKNGITCE----------GDCYM 285
                   .:||....|.||   .|||...   .|.|..||:  .||.:|:          |.|
  Rat   827 -------GSLGLAQPCHPD---AHCVIQEGVARCVCHDGFE--GNGFSCKRSSPCSHPDRGGC-- 877

  Fly   286 TCENGFCA----NKTTCVCQNGYRYDKNTTTCLPDCGDNCDNG-----VC--ISPG--NCRCFKG 337
             .||..|.    ....|:|..|:..|......:.:||.:...|     :|  :.||  .|.|..|
  Rat   878 -SENAECVPGDLGTHQCICHKGWSGDGRICVAIDECGLDTRGGCHADALCSYVGPGQSRCTCKLG 941

  Fly   338 YVRNRERCEAV--C---VGGCGFYGKCIA----PNVCGC 367
            :..:...|..:  |   .|||.....|.|    ..||.|
  Rat   942 FAGDGYECSPIDPCRVGNGGCHGLATCKAVGGGQRVCTC 980

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
NimB4	NP_788046.1	None
Stab1	XP_008769275.1	Fasciclin	391..494	CDD:295423
		Fasciclin	523..647	CDD:280607
		EGF_3	834..863	CDD:289699	12/33 (36%)
		EGF_3	918..949	CDD:289699	7/30 (23%)
		EGF_3	955..991	CDD:289699	9/26 (35%)
		Fasciclin	<1100..1180	CDD:280607
		Fasciclin	1224..1313	CDD:295423
		EGF_3	1519..1555	CDD:289699
		EGF_3	1561..1595	CDD:289699
		EGF_3	1604..1641	CDD:289699
		Fasciclin	1666..1770	CDD:280607
		Fasciclin	1796..1926	CDD:280607
		EGF_Lam	2037..2082	CDD:238012
		EGF_3	2154..2189	CDD:289699
		EGF_3	2195..2232	CDD:289699
		Link_Domain	2267..2359	CDD:295393
		FAS1	2426..2521	CDD:214719
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1218
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900