DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment NimB1 and SCARF1

DIOPT Version :9

Sequence 1:	NP_001260452.1	Gene:	NimB1 / 34813	FlyBaseID:	FBgn0027929	Length:	403	Species:	Drosophila melanogaster
Sequence 2:	NP_003684.2	Gene:	SCARF1 / 8578	HGNCID:	16820	Length:	830	Species:	Homo sapiens

Alignment Length:	391	Identity:	102/391 - (26%)
Similarity:	129/391 - (32%)	Gaps:	146/391 - (37%)

- Green bases have known domain annotations that are detailed below.

  Fly    49 SQTRERQQHLCHREVPSVFFQTERDSPVRGNGSTIYFHRIEVCCAGYRRDPYANEC-VPDCSASS 112
            |:...:.||:|....||...|                     ||||:|:..  .|| :|.|  ..
Human    20 SELDPKGQHVCVASSPSAELQ---------------------CCAGWRQKD--QECTIPIC--EG 59

  Fly   113 PDNC-RNGFCRSPGVCECFAEFVRNEHGA--------------CIHTCPIACQ-HGRCY-LNGTC 160
            ||.| ::..|..||:|.|...|    .||              |..:||  |. ||:|. ..|.|
Human    60 PDACQKDEVCVKPGLCRCKPGF----FGAHCSSRCPGQYWGPDCRESCP--CHPHGQCEPATGAC 118

  Fly   161 VCHQNFVLDQETRQFCRPKCSQSCGTHEEC-VAPGQCDCSPGYRRTPDLGCQPVCAPDCGFGKC- 223
            .|       |..|...|.:...:||.|..| .|.|.|.|.||:..:.   |:..|..:....:|
Human   119 QC-------QADRWGARCEFPCACGPHGRCDPATGVCHCEPGWWSST---CRRPCQCNTAAARCE 173

  Fly   224 VAPNQCECFAGFIKRPNW--NVCEAECYLNCENGLCE-SRYKCHCREGYRYDVNTTSCLPECSDN 285
            .|...|.|      :|.|  ..|...|  ||....|| ...:|.||.|:        ..|||...
Human   174 QATGACVC------KPGWWGRRCSFRC--NCHGSPCEQDSGRCACRPGW--------WGPECQQQ 222

  Fly   286 CGQGNGVC-IAPGVCRC---FRGYEV--------HGAECRPKCESRFCGKYGRCVAPEIC----- 333
            |....|.| .|.|.|.|   |||...        ||.:|...|        |||...|.|
Human   223 CECVRGRCSAASGECTCPPGFRGARCELPCPAGSHGVQCAHSC--------GRCKHNEPCSPDTG 279

  Fly   334 -------------------------GCGEGQQHCRNG-SCD-DIEHCS--------------CPS 357
                                     .|.:...|||:| :|: |..||.              ||:
Human   280 SCESCEPGWNGTQCQQPCLPGTFGESCEQQCPHCRHGEACEPDTGHCQRCDPGWLGPRCEDPCPT 344

  Fly   358 G 358
            |
Human   345 G 345

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
NimB1	NP_001260452.1	None
SCARF1	NP_003684.2	CSRNP_N	<100..135	CDD:292638	12/43 (28%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	516..539
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	581..688
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	715..830
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1218
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810