DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment NimB1 and Pear1

DIOPT Version :9

Sequence 1:	NP_001260452.1	Gene:	NimB1 / 34813	FlyBaseID:	FBgn0027929	Length:	403	Species:	Drosophila melanogaster
Sequence 2:	NP_001027585.1	Gene:	Pear1 / 73182	MGIID:	1920432	Length:	1034	Species:	Mus musculus

Alignment Length:	329	Identity:	89/329 - (27%)
Similarity:	124/329 - (37%)	Gaps:	82/329 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    91 CCAGYRRDPYANECVPDCSASSPDNCRN-GFC-RSPGVCECFAEFVRNEHGACIHTCPIA----- 148
            |..|:    :...|..:|      .|.| |.| |..|.|.|...::.:.   |...||:.
Mouse   261 CPEGF----HGPNCTQEC------RCHNGGLCDRFTGQCHCAPGYIGDR---CQEECPVGRFGQD 312

  Fly   149 ------CQHG-RCY-LNGTCVCHQNFVLDQETRQFCRP-----KCSQSC---GTHEECVAP--GQ 195
                  |..| ||: .||.|:|...|..|:.|.:.|..     .|.:.|   ..|.....|  |:
Mouse   313 CAETCDCAPGARCFPANGACLCEHGFTGDRCTERLCPDGRYGLSCQEPCTCDPEHSLSCHPMHGE 377

  Fly   196 CDCSPGY----------RRTPDLGCQPVCAPDCGFGKCVAPN-QCECFAGFIKRPNWNVCEAECY 249
            |.|.||:          :.|...|||..|....| |.|:|.: .|.|..|:......|:|..:.|
Mouse   378 CSCQPGWAGLHCNESCPQDTHGPGCQEHCLCLHG-GLCLADSGLCRCAPGYTGPHCANLCPPDTY 441

  Fly   250 -LNCENGL-CESRYKCH-------CREGYRYDVNTTSC-LPECSDNCGQG-----NGVCIAP--G 297
             :||.:.. ||:...|.       |:||::....:..| |.....||...     :||| :|  |
Mouse   442 GINCSSRCSCENAIACSPIDGTCICKEGWQRGNCSVPCPLGTWGFNCNASCQCAHDGVC-SPQTG 505

  Fly   298 VCRCFRGYEVHGAECRPKCESRFCGKYGRCVAPEICGCG--------EGQQHCRNGSCDDIEHCS 354
            .|.|..|:  |||.|:..|..   |::|...| .:|.|.        .||..|:.|......|..
Mouse   506 ACTCTPGW--HGAHCQLPCPK---GQFGEGCA-SVCDCDHSDGCDPVHGQCRCQAGWMGTRCHLP 564

  Fly   355 CPSG 358
            ||.|
Mouse   565 CPEG 568

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
NimB1	NP_001260452.1	None
Pear1	NP_001027585.1	EMI	25..93	CDD:284877
		EGF_CA	535..580	CDD:304395	10/34 (29%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	823..883
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	925..1034
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1218
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810