DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment NimB1 and Stab2

DIOPT Version :9

Sequence 1:NP_001260452.1 Gene:NimB1 / 34813 FlyBaseID:FBgn0027929 Length:403 Species:Drosophila melanogaster
Sequence 2:XP_038934441.1 Gene:Stab2 / 282580 RGDID:628822 Length:2569 Species:Rattus norvegicus


Alignment Length:384 Identity:102/384 - (26%)
Similarity:130/384 - (33%) Gaps:134/384 - (34%)


- Green bases have known domain annotations that are detailed below.


  Fly    56 QHLCHREVPSVFFQTERDSPVRGNGSTIYFHRIEVCCAGYRRDPYANECVPDCSA--SSPDN-CR 117
            |:||     ::..||.|                  ||.||        .:|||.|  ..||. |.
  Rat  1942 QNLC-----TLVIQTPR------------------CCHGY--------FMPDCQACPGGPDTPCN 1975

  Fly   118 N-GFCR---SP-GVCECFAEFVRNEHGACIHTCPIACQHGRCYLNGTCVCHQNFVLDQETRQFCR 177
            | |.||   :| |.|.|...|    :|.   .|.: |.|||            |..|      |:
  Rat  1976 NRGMCRDLYTPMGQCLCHTGF----NGT---ACEL-CWHGR------------FGPD------CQ 2014

  Fly   178 PKCSQSCGTHEEC----VAPGQCDCSPGYR----RTPDLGCQPVCAPDCG-FGKCVAPNQCECFA 233
            | |  ||..|.:|    ...|:|.|..|:.    .|| ....|||.|.|. ...|...|.|.|  
  Rat  2015 P-C--SCSEHGQCDEGITGSGECLCETGWTGRFCDTP-TAVIPVCTPVCSVHATCTENNTCVC-- 2073

  Fly   234 GFIKRPNWN------VCEAECYLNCENGLCE---------SRYKCHCREGYRYDVNTTSCLPECS 283
                  |.|      .|....:....||.|.         ::..|.|::||:.|  ..||:.  .
  Rat  2074 ------NLNYEGDGLTCTVVDFCKQNNGGCAKVAKCSQKGTQVSCSCKKGYKGD--GYSCIE--I 2128

  Fly   284 DNCGQG-NGVCIAPGVCRCFRGYEVHGAECRPKCESRFCGKYGRCVAPEI----CGCGEGQQHCR 343
            |.|..| ||.|.....|| ..|...|..||:    |.:.|....|...::    |....||.| .
  Rat  2129 DPCADGVNGGCHEHATCR-MTGPGKHKCECK----SHYVGDGVDCEPEQLPLDRCLQDNGQCH-P 2187

  Fly   344 NGSCDDIEHCSCPSGETHFIDRCLKADRLSQHLNTSEKRKH-----------FNRQLAY 391
            :.||.|:.......|..|.      ...|.|:..|.:|.|.           :| ||:|
  Rat  2188 DASCADLHFQDTTVGVFHL------RSPLGQYKLTFDKAKEACAKEAATIATYN-QLSY 2239

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
NimB1NP_001260452.1 None
Stab2XP_038934441.1 EGF_CA 254..283 CDD:419698
EGF_3 334..369 CDD:403986
Fasciclin 390..512 CDD:396845
Fasciclin 533..658 CDD:396845
EGF_3 840..868 CDD:403986
EGF_3 881..912 CDD:403986
EGF_3 923..955 CDD:403986
EGF_3 961..997 CDD:403986
Fasciclin 1014..1133 CDD:396845
Fasciclin 1152..1269 CDD:396845
EGF_3 1478..1514 CDD:403986
EGF_3 1520..1556 CDD:403986
EGF_3 1562..1598 CDD:403986
Fasciclin 1629..1729 CDD:396845
Fasciclin 1754..1885 CDD:396845
EGF_CA 2059..2084 CDD:419698 7/32 (22%)
EGF_3 2090..2125 CDD:403986 8/36 (22%)
EGF_3 2131..2168 CDD:403986 13/41 (32%)
Link_Domain 2202..2294 CDD:413401 11/45 (24%)
FAS1 2360..2449 CDD:214719
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG1218
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.900

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