DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment NimB1 and Tnfaip6

DIOPT Version :9

Sequence 1:	NP_001260452.1	Gene:	NimB1 / 34813	FlyBaseID:	FBgn0027929	Length:	403	Species:	Drosophila melanogaster
Sequence 2:	NP_033424.1	Gene:	Tnfaip6 / 21930	MGIID:	1195266	Length:	275	Species:	Mus musculus

Alignment Length:	248	Identity:	48/248 - (19%)
Similarity:	73/248 - (29%)	Gaps:	112/248 - (45%)

- Green bases have known domain annotations that are detailed below.

  Fly   151 HGRCYLNGTCVCHQNFVLDQ-------------------ETRQFC-----------RPKCSQSCG 185
            ||..:.||  :.|.:..|:|                   |.:..|           :.:.::..|
Mouse    16 HGWGFKNG--IFHNSIWLEQAAGVYHREARAGRYKLTYAEAKAVCEFEGGRLATYKQLEAARKIG 78

  Fly   186 THEECVAPGQCDCSPGYRRTPDLGCQPVC--APDCGFGK-------------------CVAPNQC 229
            .|.         |:.|:.....:| .|:.  .|:|||||                   |..|:..
Mouse    79 FHV---------CAAGWMAKGRVG-YPIVKPGPNCGFGKTGIIDYGIRLNRSERWDAYCYNPHAK 133

  Fly   230 ECFAGFI--KR-------PNWNVCEAECYLNCENGLCESRYKCHCREGYRYDVNTTSCLPECSDN 285
            ||...|.  ||       ||.......||             .|.|..|...::.:....:...:
Mouse   134 ECGGVFTDPKRIFKSPGFPNEYDDNQVCY-------------WHIRLKYGQRIHLSFLDFDLEHD 185

  Fly   286 CGQGNGVCIAPGVCRCFRGY-EVHGAECRPKCESRFCGKYGRCVAPEICGCGE 337
            .|     |:|..| ..:..| :|||          |.|:|          ||:
Mouse   186 PG-----CLADYV-EIYDSYDDVHG----------FVGRY----------CGD 212

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
NimB1	NP_001260452.1	None
Tnfaip6	NP_033424.1	Link_domain_TSG_6_like	36..128	CDD:239592	14/101 (14%)
		CUB	135..244	CDD:278839	24/117 (21%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	253..275
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1218
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900