DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment NimB1 and Dkk1

DIOPT Version :9

Sequence 1:	NP_001260452.1	Gene:	NimB1 / 34813	FlyBaseID:	FBgn0027929	Length:	403	Species:	Drosophila melanogaster
Sequence 2:	NP_034181.2	Gene:	Dkk1 / 13380	MGIID:	1329040	Length:	272	Species:	Mus musculus

Alignment Length:	203	Identity:	50/203 - (24%)
Similarity:	71/203 - (34%)	Gaps:	63/203 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly   191 VAPGQCDCSPGYRRTPDLGCQPV-CAPD--CGFGK-CVAPNQCECFAGFIKRPNWNVCEA----- 246
            ||||.........:|.| ..||. ||.|  ||..: |.:|::.....|.::     :|.|
Mouse    63 VAPGVLYEGGNKYQTLD-NYQPYPCAEDEECGSDEYCSSPSRGAAGVGGVQ-----ICLACRKRR 121

  Fly   247 -ECYLN--------CENGLCESRYKCH---------------------CREGYRYDVNTTSCLPE 281
             .|..:        |:||:|......|                     ..:||......||.:..
Mouse   122 KRCMRHAMCCPGNYCKNGICMPSDHSHFPRGEIEESIIENLGNDHNAAAGDGYPRRTTLTSKIYH 186

  Fly   282 CSDNCGQGNGVCI-----APGVCRCFRGYEVHGAECRPKC-ESRFCGKYGRCVAPEI-----CGC 335
            ..   ||...||:     |.|:| |.|.:  ....|:|.. |.:.|.|:.|..:..:     |.|
Mouse   187 TK---GQEGSVCLRSSDCAAGLC-CARHF--WSKICKPVLKEGQVCTKHKRKGSHGLEIFQRCYC 245

  Fly   336 GEGQQHCR 343
            |||.. ||
Mouse   246 GEGLA-CR 252

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
NimB1	NP_001260452.1	None
Dkk1	NP_034181.2	Dickkopf_N	86..142	CDD:282549	14/60 (23%)
		DKK-type Cys-1	86..141		14/59 (24%)
		DKK-type Cys-2	195..269		19/62 (31%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1218
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900