DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment NimB1 and pear1

DIOPT Version :9

Sequence 1:	NP_001260452.1	Gene:	NimB1 / 34813	FlyBaseID:	FBgn0027929	Length:	403	Species:	Drosophila melanogaster
Sequence 2:	XP_017952446.2	Gene:	pear1 / 100489801	XenbaseID:	XB-GENE-6045593	Length:	1087	Species:	Xenopus tropicalis

Alignment Length:	392	Identity:	105/392 - (26%)
Similarity:	136/392 - (34%)	Gaps:	146/392 - (37%)

- Green bases have known domain annotations that are detailed below.

  Fly    82 TIYFHRIEV-------CCAGYRRDPYANE-CVPDCSASSPDNCRNGFCRSPGVCECFAEFVRNEH 138
            |.|.||:::       ||.||..   :|: |||.|:    ..|.:|.|.:|..|:|       |.
Frog    76 TAYRHRVKLDYRRRYWCCKGYYE---SNDICVPRCT----QECVHGRCIAPDQCQC-------EP 126

  Fly   139 G-----------------ACIHTCPIACQ-HGRC-YLNGTCVCHQNFVLDQETRQFCRP-----K 179
            |                 .|..|||  || :|.| ..:|||:|...| .|....:.|.|     .
Frog   127 GWRGKDCSSACEAHVWGPKCNSTCP--CQNNGACDAASGTCICPPGF-RDPFCEKPCDPGTYGGG 188

  Fly   180 CSQSCGTHEECVAPGQCDCSPGYRRTPDLGCQPVCAPDCGFGKCVAP------NQCECFAGFIKR 238
            ||.||    :|....:||...|....|:....|.|...|   |.|.|      :||.|.:|.|..
Frog   189 CSLSC----QCKNGAECDPENGACLCPEGYTGPYCEIRC---KEVQPANFSCSDQCLCQSGGICN 246

  Fly   239 ---------PNW---------------NVCEAECYLNCEN-GLCESRY-KCHCREGYRYDVNTTS 277
                     |.|               ..|:.||.  |.| |.|:.:. :|.|.|||..|.....
Frog   247 QSSGECSCPPGWMGSLCSIPCPDGYYGRNCKQECL--CHNGGQCDPKTGQCLCSEGYTGDHCREE 309

  Fly   278 CLP------ECSDNCGQGNGV-CI-APGVCRCFRGYEVHGAECRPKCESRFC--GKYG-----RC 327
            | |      :||:.|...|.| |. ..|.|.|..|::...      |:.|.|  |.||     ||
Frog   310 C-PIGKYGKDCSEKCDCINAVRCYHINGGCLCEHGFKGEA------CDERMCPPGLYGMPCNLRC 367

  Fly   328 VAPEI-----------CGCGEG-------------------QQHC---RNGSCD-DIEHCSCPSG 358
            :...:           |.|..|                   |:.|   ..|||| :...|.|..|
Frog   368 LCDPLHSQSCHPMSGECACKPGWSGLYCNETCPHGYYGTNCQELCVCLNGGSCDSETGECICAPG 432

  Fly   359 ET 360
            .|
Frog   433 FT 434

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
NimB1	NP_001260452.1	None
pear1	XP_017952446.2	EMI	29..97	CDD:400092	7/20 (35%)
		exchanger_TraA	<147..>310	CDD:411343	50/174 (29%)
		exchanger_TraA	<416..729	CDD:411343	8/19 (42%)
		Laminin_EGF	546..586	CDD:395007
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910