DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Vajk3 and Zfp512b

DIOPT Version :9

Sequence 1:	NP_609690.1	Gene:	Vajk3 / 34812	FlyBaseID:	FBgn0028544	Length:	277	Species:	Drosophila melanogaster
Sequence 2:	NP_001158069.1	Gene:	Zfp512b / 269401	MGIID:	2685478	Length:	869	Species:	Mus musculus

Alignment Length:	253	Identity:	67/253 - (26%)
Similarity:	102/253 - (40%)	Gaps:	47/253 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    14 SACASKTEGEKVPLEKKLDKRGLLDLGYGYGHAGLDTGYLGHGSISGHGS-----YGHGYGL--- 70
            ::.:.||||:|.. ..|.:.:.|.|:.....:...|. :..|..:....|     :...|||
Mouse    64 NSASDKTEGKKKG-RPKAENQALRDIPLSLMNQWKDE-FKAHSRVKCPNSGCWLEFPSIYGLKYH 126

  Fly    71 ------------TGYSAPAAVAVGHSGPAIA-------VGHTAPAVAVHHAPAPYVISKQADVHK 116
                        ..:..|...|...|...:.       :.|..||........|..||:...|.|
Mouse   127 YQRCQGGAISDRLAFPCPFCEAAFTSKTQLEKHRIWNHMDHPLPAPKPGPVSRPVTISRPVGVSK 191

  Fly   117 TITITKGIPV--PVHVDRPY----PVVHEKRVPVEVKVPVPQPYEVIRKVPVTVKEYVKVPVPVP 175
            .|.::|.:.|  ||.|.:|.    ||...:.:||...|.|.:|.:|.|.||||      .|:|:.
Mouse   192 PIGVSKPVTVGKPVGVSKPIGISKPVTVSRPIPVTKPVTVSRPMQVSRPVPVT------KPIPIT 250

  Fly   176 QPYEVIRHEKVPVHVPVDRPVPVEVPRPYPVPVAKPYPVYVEKAVNVQVPVHVDRPYP 233
            :|..:.:|..|...|.|.:|||:    ..||||::  |:.|.|.|.|..|:.:.|..|
Mouse   251 KPVPLTKHMPVTKLVTVSKPVPL----TKPVPVSR--PIVVSKPVPVSRPIAISRHIP 302

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Vajk3	NP_609690.1	None
Zfp512b	NP_001158069.1	PRK12323	<170..425	CDD:237057	49/145 (34%)
		C2H2 Zn finger	573..594	CDD:275368
		C2H2 Zn finger	609..630	CDD:275368
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167841129
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E33208_3BHSB
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.740