Protein Alignment Vajk2 and GGN

DIOPT Version :10

• Sequence 1: NP_609689.3
• Gene: Vajk2 / 34811
• FlyBaseID: FBgn0032538
• Length: 270
• Species: Drosophila melanogaster
• Sequence 2: NP_689870.3
• Gene: GGN / 199720
• HGNCID: 18869
• Length: 652
• Species: Homo sapiens
• Alignment Length: 262
• Identity: 64/262 - (24%)
• Similarity: 92/262 - (35%)
• Gaps: 72/262 - (27%)

  Fly    20 SEEAP-KKAVETAEPAEKKQEKRGIGHGLGYGYGPSAGGAILGSGIGVGVPVAPAVAELPTQVHT 83
            |:.|| .:.....||....|..| :..|||..:..||      :..|:.||..|       |...
Human    20 SDRAPDSRRTSLVEPEMTSQAMR-LTRGLGVWFPGSA------TPPGLMVPREP-------QASP 70

  Fly    84 NTVVRTVQVPYQVERHVPYPVEKTVTYPVKVPVPQPYPVEKIVHVPVKQIVKVPVEVPQPYPVEK 148
            :|:..|::.|..|   :|.|.|...     |..|.|.|...::..|.|.      :.|...||.:
Human    71 STLPLTLERPSPV---MPPPEEAAA-----VSAPPPAPAGTLLPGPSKW------QKPAGTPVPR 121

  Fly   149 VIRV----------PVKIPVDRPYTVHVDKPYPVPVEKPVPYTVEKRVIHKVPVHVE--RPVPYK 201
            :.|:          |   |..||.     ||.|.|.:..|..|| .|...:.|..:|  :|.|
Human   122 IRRLLEASHRGQGDP---PSLRPL-----KPPPPPRQLSVKDTV-PRAPSQFPPPLETWKPPP-- 175

  Fly   202 VAVPVPVH---VESHVKPAVAVTHTVAAAPAIISHGYSGHGISGYGISGHGISSYGSSSYGGSAH 263
               |:|..   .:..:.||:|   |.|:.|.....|....|           .:.|.:..|...|
Human   176 ---PLPSERQPADRRITPALA---TPASPPTESQAGPRNQG-----------QTAGRARGGAPPH 223

  Fly   264 GG 265
            .|
Human   224 AG 225

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Vajk2	NP_609689.3	rne	<69..236	CDD:236766	45/181 (25%)
GGN	NP_689870.3	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..39		5/18 (28%)
		GGN	2..652	CDD:434857	64/262 (24%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	52..237		54/229 (24%)
		Interaction with GGNBP1. /evidence=ECO:0000250	123..486		31/131 (24%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	251..273
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	291..473
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	488..576
		Interactions with ZNF403/GGNBP2 and OAZ3. /evidence=ECO:0000250	491..652