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Protein Alignment Ance-3 and Ace2

DIOPT Version :9

Sequence 1:	NP_001033904.1	Gene:	Ance-3 / 34808	FlyBaseID:	FBgn0032536	Length:	844	Species:	Drosophila melanogaster
Sequence 2:	NP_001123985.1	Gene:	Ace2 / 70008	MGIID:	1917258	Length:	805	Species:	Mus musculus

Alignment Length:	616	Identity:	209/616 - (33%)
Similarity:	333/616 - (54%)	Gaps:	44/616 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly   206 YQQELEKLRILLVESDQKGSLECTANVAAQWNFETNVNDFTQTEALNAQQRYVEFQRITAEQSKR 270
            :.||.|.|       ..:.||       |.||:.||:   |:..|....:...::.....||||.
Mouse    32 FNQEAEDL-------SYQSSL-------ASWNYNTNI---TEENAQKMSEAAAKWSAFYEEQSKT 79

  Fly   271 INKDLIFDRR---LYRQLMLQSEVGPNALPLDVLDRYNRLLNEMLFLYNSAEICAYQQPFQCDLH 332
            .....:.:.:   :.|||....:.|.:||..|...:.|.:||.|..:|::.::|..:.|.:| |.
Mouse    80 AQSFSLQEIQTPIIKRQLQALQQSGSSALSADKNKQLNTILNTMSTIYSTGKVCNPKNPQEC-LL 143

  Fly   333 YIPQLKDIMAKSRDWDELQHTWVEYHRKAGRGMRDSYEQLIDVMQEVAYVNNVTNGGEYWYLAYE 397
            ..|.|.:|||.|.|::.....|..:..:.|:.:|..||:.:.:..|:|..||..:.|:||...||
Mouse   144 LEPGLDEIMATSTDYNSRLWAWEGWRAEVGKQLRPLYEEYVVLKNEMARANNYNDYGDYWRGDYE 208

  Fly   398 SG-----NFR-----QDMDIVWEQIRPLYEGLHAYVRRKLRDYYGPDRINRIAPIPSHILGNMYG 452
            :.     |:.     :|::..:.:|:||||.|||||||||.|.| |..|:....:|:|:||:|:|
Mouse   209 AEGADGYNYNRNQLIEDVERTFAEIKPLYEHLHAYVRRKLMDTY-PSYISPTGCLPAHLLGDMWG 272

  Fly   453 QSWSNVLDILIPYPGRKLIDVTPRMVEQGYTPQLMFQLAEEFFTSINMSAVGPEFYRNSIFEQPL 517
            :.|:|:..:.:|:..:..||||..|:.||:..:.:||.||:||.|:.:..:...|:.||:..:|.
Mouse   273 RFWTNLYPLTVPFAQKPNIDVTDAMMNQGWDAERIFQEAEKFFVSVGLPHMTQGFWANSMLTEPA 337

  Fly   518 D-RRVLCEPSAWDFCNRHDFRVKICTDINQRSLISVHHEMAHIQYFLQYRHLPKIFRNGANPAFH 581
            | |:|:|.|:|||. ...|||:|:||.:...:.::.||||.||||.:.|...|.:.|||||..||
Mouse   338 DGRKVVCHPTAWDL-GHGDFRIKMCTKVTMDNFLTAHHEMGHIQYDMAYARQPFLLRNGANEGFH 401

  Fly   582 QAVGDAIGLSVSTPRHLQTLGLLQRSLDE-SSYDINYLFTMAIDKVAFLPFALSLDNWRYDVFSG 645
            :|||:.:.||.:||:||:::|||.....| |..:||:|...|:..|..|||...|:.||:.||.|
Mouse   402 EAVGEIMSLSAATPKHLKSIGLLPSDFQEDSETEINFLLKQALTIVGTLPFTYMLEKWRWMVFRG 466

  Fly   646 NANKRTMNCHYWNLREKYSGIKPPVLRSEKDFDPGAKYHIPANIPYIKYFFSTVLQFQIYRGLCR 710
            ...|......:|.::.:..|:..|:...|...||.:.:|:..:..:|:|:..|:.|||....||
Mouse   467 EIPKEQWMKKWWEMKREIVGVVEPLPHDETYCDPASLFHVSNDYSFIRYYTRTIYQFQFQEALC- 530

  Fly   711 ESGQYVPGDPRKPLHQCDIYRQPAAGNILKTLMSKGASQPWQEVLEETLREGRLDGTALREYFAP 775
            ::.:|     ...||:|||.....||..|..::|.|.|:||.:.||..:....:|...|..||.|
Mouse   531 QAAKY-----NGSLHKCDISNSTEAGQKLLKMLSLGNSEPWTKALENVVGARNMDVKPLLNYFQP 590

  Fly   776 LEEWLRQENLRTNEYVGWNYD-GDYCKRSIE 805
            |.:||:::|  .|.:||||.: ..|..:||:
Mouse   591 LFDWLKEQN--RNSFVGWNTEWSPYADQSIK 619

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.