Protein Alignment Ance-3 and ace2

DIOPT Version :10

• Sequence 1: NP_001033904.1
• Gene: Ance-3 / 34808
• FlyBaseID: FBgn0032536
• Length: 844
• Species: Drosophila melanogaster
• Sequence 2: NP_001007298.2
• Gene: ace2 / 492331
• ZFINID: ZDB-GENE-041114-6
• Length: 818
• Species: Danio rerio
• Alignment Length: 595
• Identity: 218/595 - (36%)
• Similarity: 327/595 - (54%)
• Gaps: 19/595 - (3%)

  Fly   211 EKLRILLVESDQKGSLECTANVAAQWNFETNVNDFTQTEALNAQQRYVEFQRITAEQSKRINKDL 275
            ::.|..|.:.|::.|........|.|.:.|:::.....:...|...:.|:....:|:|.....|.
Zfish    22 DRAREFLNKFDEEASDIMYQYTLASWAYNTDISQENADKEAEAYAIWSEYYNKMSEESNAYPIDQ 86

  Fly   276 IFDRRLYRQLMLQSEVGPNALPLDVLDRYNRLLNEMLFLYNSAEICAYQQPFQCDLHYIPQLKDI 340
            |.|..:..||....:.|..||..|.......:::||..:||:|.:|....|..|.. ..|.|:.|
Zfish    87 ISDPIIKMQLQKLQDKGSGALSPDKASELRNIMSEMSTIYNTATVCKIDDPTDCQT-LEPGLESI 150

  Fly   341 MAKSRDWDELQHTWVEYHRKAGRGMRDSYEQLIDVMQEVAYVNNVTNGGEYWYLAYES-----GN 400
            ||:|||:||..|.|..:....|..||..||:.:|:..|.|.:||..:.|:||...||:     .:
Zfish   151 MAESRDYDERLHVWEGWRVATGMKMRPLYEKYVDLKNEAAKLNNYEDHGDYWRGDYETIDDPKYS 215

  Fly   401 FRQDMDI-----VWEQIRPLYEGLHAYVRRKLRDYYGPDRINRIAPIPSHILGNMYGQSWSNVLD 460
            :.:|..|     ::::|.|||:.||||||.||:|.| |..|...|.:|:|:||:|:|:.|:|:..
Zfish   216 YSRDQVIEDARRIYKEILPLYKELHAYVRAKLQDVY-PGHIGSDACLPAHLLGDMWGRFWTNLYP 279

  Fly   461 ILIPYPGRKLIDVTPRMVEQGYTPQLMFQLAEEFFTSINMSAVGPEFYRNSIFEQPLDRRVLCEP 525
            ::||||.|..|||:..|||||:....:|:.||:||.|:||.|:...|:.||:|.:|.:|.|:|.|
Zfish   280 LMIPYPDRPDIDVSSAMVEQGWDEIRLFKEAEKFFMSVNMPAMFDNFWNNSMFIKPEERDVVCHP 344

  Fly   526 SAWDFCNRHDFRVKICTDINQRSLISVHHEMAHIQYFLQYRHLPKIFRNGANPAFHQAVGDAIGL 590
            :|||..||.|||:|:||.:|....::|||||.|.||.:.||:.|.:.|:|||..||:|||:.:.|
Zfish   345 TAWDMGNRKDFRIKMCTKVNMDDFLTVHHEMGHNQYQMAYRNHPYLLRDGANEGFHEAVGEIMSL 409

  Fly   591 SVSTPRHLQTLGLLQRSLDES-SYDINYLFTMAIDKVAFLPFALSLDNWRYDVFSGNANKRTMNC 654
            |.:||.|||:||||.....:. ..|||:|...|:..|..|||...|:.||:.||.....|.....
Zfish   410 SAATPSHLQSLGLLPSDFKQDYETDINFLLKQALTIVGTLPFTYMLEEWRWQVFKAKIPKDEWMQ 474

  Fly   655 HYWNLREKYSGIKPPVLRSEKDFDPGAKYHIPANIPYIKYFFSTVLQFQIYRGLCRESGQYVPGD 719
            .:|.::.:..|:...|.|.|...||.|.:|:..:..:|:||..|:.|||....||:.:|.
Zfish   475 QWWQMKRELVGVAEAVPRDETYCDPPALFHVSGDYSFIRYFTRTIYQFQFQEALCKAAGH----- 534

  Fly   720 PRKPLHQCDIYRQPAAGNILKTLMSKGASQPWQEVLEETLREGRLDGTALREYFAPLEEWLRQEN 784
             ..||::|||.....||:.|:.::..|.|..|...|||.....::|...|..||:.|.|||::||
Zfish   535 -TGPLYKCDITNSTKAGDKLRHMLELGRSMSWTRALEEVAGTTKMDSQPLLHYFSTLMEWLKEEN 598

  Fly   785 LRTNEYVGWN 794
            .:.|...|||
Zfish   599 QKNNRVPGWN 608

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ance-3	NP_001033904.1	M2_ACE	216..784	CDD:341055	211/578 (37%)
ace2	NP_001007298.2	None