Protein Alignment Ance-3 and Ance-2

DIOPT Version :9

• Sequence 1: NP_001033904.1
• Gene: Ance-3 / 34808
• FlyBaseID: FBgn0032536
• Length: 844
• Species: Drosophila melanogaster
• Sequence 2: NP_788042.1
• Gene: Ance-2 / 34806
• FlyBaseID: FBgn0032535
• Length: 611
• Species: Drosophila melanogaster
• Alignment Length: 623
• Identity: 174/623 - (27%)
• Similarity: 278/623 - (44%)
• Gaps: 63/623 - (10%)

  Fly   215 ILLVESDQKGS-----LECTANVAAQWNFETN---------------VNDFTQTEALNA------ 253
            :|||...|.||     ||...|       |||               :|:......|.|
  Fly     7 LLLVGLTQAGSQPDATLERFLN-------ETNQQLAVIYDQAVLAQLLNELRGPNDLVALLEIEV 64

  Fly   254 -QQRYVEFQRITAEQSKRINKDLIFDRRLYRQLMLQSEVGPNALPLDVLDRYNRLLNEMLFLYNS 317
             ..:.|::.|....:..:..:..:.|.|..|.|....::|..||....|.....|.:.|...|::
  Fly    65 TDDKLVKYVRTLTTRKAKFKRLGLGDSRQRRLLDKIPQLGYEALSGRDLKLVYALASSMSDNYHN 129

  Fly   318 AEICAYQQPFQCDLHYIPQLKDIMAKSRDWDELQHTWVEYHRKAGRGMRDSYEQLIDVMQEVAYV 382
            .::|||:||..|.|..||:::.|:..|||.||:::.|.|:..:.|...|..:...:|:.::.|.:
  Fly   130 VKLCAYKQPGNCTLRLIPEVQSIVQGSRDLDEIEYYWFEWRSRTGLATRSQFVDFMDLYKKTAQL 194

  Fly   383 NNVTNGGEYWYLAYE-SGNFRQD-MDIVWEQIRPLYEGLHAYVRRKLRDYYGPDRINRIAPIPSH 445
            |......:||:.:.| .|....: :|.:...:|||:...||:||..||..:|...:.|..|.|.|
  Fly   195 NGYPRAEDYWFRSLELKGQETMNLLDRIMHGLRPLFLQFHAHVRGSLRKMHGEHLVPRNRPYPQH 259

  Fly   446 I----LGNMYGQ---SWSNVLDILIPYPGRKLIDVTPRMVEQGY-TPQLMFQLAEEFFTSINMSA 502
            :    :||.:.:   .|.    :.:|.|...|.::|..:..:|. |.|.:|....|:|.::..
  Fly   260 LAEVFIGNAFRRVEAEWY----VDLPSPEIGLANITQELHRRGLSTTQRVFWNVAEYFRALGF-- 318

  Fly   503 VGPEF------YRNSIFEQPLDRRVLCEPSAWDFCNRHDFRVKICTDINQRSLISVHHEMAHIQY 561
              |:.      |...:.....||   |...||.:..........|...::....::....:.:||
  Fly   319 --PQLENSLWTYAQKVSSDDDDR---CWHKAWRYYALPRTNFTYCPLNDEERFFNMFEAQSDLQY 378

  Fly   562 FLQYRHLPKIFRNGANPAFHQAVGDAIGLSVSTPRHLQTLGLLQ-RSLDESSYDINYLFTMAIDK 625
            :......|.:.:....|.|..|:|....::.|:||.|:.||:|: ....|....:|.|:...:..
  Fly   379 YRAASIQPTLLQEEPFPNFSDAIGKCFSMAASSPRFLRKLGMLRDNKWKELPARLNRLYIQGLRV 443

  Fly   626 VAFLPFALSLDNWRYDVFSGNANKRTMNCHYWNLREKYSGIKPPVLRSEKDFDPGAKYHIPANIP 690
            |..||....||.:|.:|.:|:. |...|..||.|.|.|:|...|..|:.:.||..||..:..:..
  Fly   444 VFLLPVFYVLDRYRVEVLAGHI-KADDNEAYWRLTELYTGAAAPTKRTNEQFDVPAKLLMEVDDQ 507

  Fly   691 YIKYFFSTVLQFQIYRGLCRESGQYVPGDPRKPLHQCDIYRQPAAGNILKTLMSKGASQPWQEVL 755
            |...|.|.|||||:.:..|..:||:..|:|||||..||:..|...|.|||..||.|:|..::|||
  Fly   508 YASNFLSIVLQFQLLKHFCTITGQFEMGNPRKPLDMCDLSDQRGIGEILKRAMSLGSSVHYREVL 572

  Fly   756 EETLREGRLDGTALREYFAPLEEWLRQENLRTNEYVGW 793
            :..|.|..:....|..||.||::||:.:|...|..|||
  Fly   573 KVLLGEPEISIDGLLTYFQPLQDWLQHQNQENNLEVGW 610

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ance-3	NP_001033904.1	M2_ACE	216..784	CDD:188999	169/611 (28%)
Ance-2	NP_788042.1	GluZincin	26..601	CDD:301352	161/593 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3690
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S5260
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D16282at33392
OrthoFinder	1	1.000	-	-		FOG0000442
OrthoInspector	1	1.000	-	-		otm14376
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR10514
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	7	6.870