DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ance-3 and Acer

DIOPT Version :9

Sequence 1:	NP_001033904.1	Gene:	Ance-3 / 34808	FlyBaseID:	FBgn0032536	Length:	844	Species:	Drosophila melanogaster
Sequence 2:	NP_001260258.1	Gene:	Acer / 34189	FlyBaseID:	FBgn0016122	Length:	630	Species:	Drosophila melanogaster

Alignment Length:	600	Identity:	233/600 - (38%)
Similarity:	349/600 - (58%)	Gaps:	18/600 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly   195 LERQRYQQDRRYQQELEKLRILLVESDQKGSLECTANVAAQWNFETNVNDFTQTEALNAQQRYVE 259
            ||.:|:     ::.|.|:||....|....|           :|:.|||.:..:...:....|..|
  Fly    32 LEARRF-----FELENEQLRRRFHEEFLSG-----------YNYNTNVTEANRQAMIEVYARNAE 80

  Fly   260 FQRITAEQSKRINKDLIFDRRLYRQLMLQSEVGPNALPLDVLDRYNRLLNEMLFLYNSAEICAYQ 324
            ..:..|:|.|..:.....|..:.||....|::|.:||..|........::.|...|.:|.:|:|.
  Fly    81 LNKRLAQQIKSSDYVQSEDADIRRQAEHLSKLGASALNADDYLALQNAISSMQTNYATATVCSYT 145

  Fly   325 QPFQCDLHYIPQLKDIMAKSRDWDELQHTWVEYHRKAGRGMRDSYEQLIDVMQEVAYVNNVTNGG 389
            ....|.|...|.:::.::.|||..||...|.|:|.|:|..||.::.:.:.:.::.:.:|...:..
  Fly   146 NRSDCSLTLEPHIQERLSHSRDPAELAWYWREWHDKSGTPMRQNFAEYVRLTRKASQLNGHRSYA 210

  Fly   390 EYWYLAYESGNFRQDMDIVWEQIRPLYEGLHAYVRRKLRDYYGPDRINRIAPIPSHILGNMYGQS 454
            :||...||..:|.:.:|..::|:.|.|..||.|||.:||.:||||.:.....||..:||||:|||
  Fly   211 DYWVQFYEDPDFERQLDATFKQLLPFYRQLHGYVRFRLRQHYGPDVMPAEGNIPISLLGNMWGQS 275

  Fly   455 WSNVLDILIPYPGRKLIDVTPRMVEQGYTPQLMFQLAEEFFTSINMSAVGPEFYRNSIFEQPLDR 519
            |:.:||:..|||.:..:||...|.:||||.|.:|:|.::||.|:.|.|:.|.|:..|:..:|.||
  Fly   276 WNELLDLFTPYPEKPFVDVKAEMEKQGYTVQKLFELGDQFFQSLGMRALPPSFWNLSVLTRPDDR 340

  Fly   520 RVLCEPSAWDFCNRHDFRVKICTDINQRSLISVHHEMAHIQYFLQYRHLPKIFRNGANPAFHQAV 584
            .|:|..|||||....|.|:|:||:::......||||:.||||:|||...|.::|...||.||:||
  Fly   341 HVVCHASAWDFYQDSDVRIKMCTEVDSHYFYVVHHELGHIQYYLQYEQQPAVYRGAPNPGFHEAV 405

  Fly   585 GDAIGLSVSTPRHLQTLGLLQRS-LDESSYDINYLFTMAIDKVAFLPFALSLDNWRYDVFSGNAN 648
            ||.|.|||.:.:||:.:||::.. |||.| .||.||..|:.|:.||||..::|.:||.||....:
  Fly   406 GDVIALSVMSAKHLKAIGLIENGRLDEKS-RINQLFKQALSKIVFLPFGYAVDKYRYAVFRNELD 469

  Fly   649 KRTMNCHYWNLREKYSGIKPPVLRSEKDFDPGAKYHIPANIPYIKYFFSTVLQFQIYRGLCRESG 713
            :...||.:|.:|.::.|::|||.|:||||||.|||||.|::.|::||.:.:.|||.::.|||::|
  Fly   470 ESQWNCGFWQMRSEFGGVEPPVFRTEKDFDPPAKYHIDADVEYLRYFAAHIFQFQFHKALCRKAG 534

  Fly   714 QYVPGDPRKPLHQCDIYRQPAAGNILKTLMSKGASQPWQEVLEETLREGRLDGTALREYFAPLEE 778
            ||.|.:.|..|..|||:...|||..|...:|||.|:.|:|||||...|..:|..||.|||.||.:
  Fly   535 QYAPNNSRLTLDNCDIFGSKAAGRSLSQFLSKGNSRHWKEVLEEFTGETEMDPAALLEYFEPLYQ 599

  Fly   779 WLRQENLRTNEYVGW 793
            ||:|||.|....:||
  Fly   600 WLKQENSRLGVPLGW 614

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ance-3	NP_001033904.1	M2_ACE	216..784	CDD:188999	221/568 (39%)
Acer	NP_001260258.1	M2_ACE	37..605	CDD:188999	225/584 (39%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	223	1.000	Domainoid score	I1460
eggNOG	1	0.900	-	-		E1_KOG3690
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	226	1.000	Inparanoid score	I2232
Isobase	1	0.950	-	0	Normalized mean entropy	S5260
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D16282at33392
OrthoFinder	1	1.000	-	-		FOG0000442
OrthoInspector	1	1.000	-	-		otm14376
orthoMCL	1	0.900	-	-		OOG6_101615
Panther	1	1.100	-	-	P	PTHR10514
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	10	9.820