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Protein Alignment Ance-3 and Ace2

DIOPT Version :9

Sequence 1:	NP_001033904.1	Gene:	Ance-3 / 34808	FlyBaseID:	FBgn0032536	Length:	844	Species:	Drosophila melanogaster
Sequence 2:	NP_001012006.1	Gene:	Ace2 / 302668	RGDID:	728890	Length:	805	Species:	Rattus norvegicus

Alignment Length:	633	Identity:	208/633 - (32%)
Similarity:	331/633 - (52%)	Gaps:	50/633 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly   192 QGYLERQRYQQDRRYQQELEKLRILLVESDQKGSLECTANVAAQWNFETNVNDFTQTEALNAQQR 256
            |..:|.:......::.||.|.|       ..:.||       |.||:.||:   |:..|....:.
  Rat    18 QSLIEEKAESFLNKFNQEAEDL-------SYQSSL-------ASWNYNTNI---TEENAQKMNEA 65

  Fly   257 YVEFQRITAEQSK---RINKDLIFDRRLYRQLMLQSEVGPNALPLDVLDRYNRLLNEMLFLYNSA 318
            ..::.....||||   ..:...|.:..:.|||....:.|.:||..|...:.|.:||.|..:|::.
  Rat    66 AAKWSAFYEEQSKIAQNFSLQEIQNATIKRQLKALQQSGSSALSPDKNKQLNTILNTMSTIYSTG 130

  Fly   319 EICAYQQPFQCDLHYIPQLKDIMAKSRDWDELQHTWVEYHRKAGRGMRDSYEQLIDVMQEVAYVN 383
            ::|....|.:|.| ..|.|.:|||.|.|::.....|..:..:.|:.:|..||:.:.:..|:|..|
  Rat   131 KVCNSMNPQECFL-LEPGLDEIMATSTDYNRRLWAWEGWRAEVGKQLRPLYEEYVVLKNEMARAN 194

  Fly   384 NVTNGGEYWYLAYESG-----NFR-----QDMDIVWEQIRPLYEGLHAYVRRKLRDYYGPDRINR 438
            |..:.|:||...||:.     |:.     :|::..:::|:||||.||||||.||.:.| |..|:.
  Rat   195 NYEDYGDYWRGDYEAEGVEGYNYNRNQLIEDVENTFKEIKPLYEQLHAYVRTKLMEVY-PSYISP 258

  Fly   439 IAPIPSHILGNMYGQSWSNVLDILIPYPGRKLIDVTPRMVEQGYTPQLMFQLAEEFFTSINMSAV 503
            ...:|:|:||:|:|:.|:|:..:..|:..:..||||..||.|.:..:.:|:.||:||.|:.:..:
  Rat   259 TGCLPAHLLGDMWGRFWTNLYPLTTPFLQKPNIDVTDAMVNQSWDAERIFKEAEKFFVSVGLPQM 323

  Fly   504 GPEFYRNSIFEQP-LDRRVLCEPSAWDFCNRHDFRVKICTDINQRSLISVHHEMAHIQYFLQYRH 567
            .|.|:.||:..:| .||:|:|.|:|||. ...|||:|:||.:...:.::.||||.||||.:.|..
  Rat   324 TPGFWTNSMLTEPGDDRKVVCHPTAWDL-GHGDFRIKMCTKVTMDNFLTAHHEMGHIQYDMAYAK 387

  Fly   568 LPKIFRNGANPAFHQAVGDAIGLSVSTPRHLQTLGLLQRSLDE-SSYDINYLFTMAIDKVAFLPF 631
            .|.:.|||||..||:|||:.:.||.:||:||:::|||..:..| :..:||:|...|:..|..|||
  Rat   388 QPFLLRNGANEGFHEAVGEIMSLSAATPKHLKSIGLLPSNFQEDNETEINFLLKQALTIVGTLPF 452

  Fly   632 ALSLDNWRYDVFSGNANKRTMNCHYWNLREKYSGIKPPVLRSEKDFDPGAKYHIPANIPYIKYFF 696
            ...|:.||:.||.....:......:|.::.:..|:..|:...|...||.:.:|:..:..:|:|:.
  Rat   453 TYMLEKWRWMVFQDKIPREQWTKKWWEMKREIVGVVEPLPHDETYCDPASLFHVSNDYSFIRYYT 517

  Fly   697 STVLQFQIYRGLC---RESGQYVPGDPRKPLHQCDIYRQPAAGNILKTLMSKGASQPWQEVLEET 758
            .|:.|||....||   :..|         |||:|||.....||..|..::|.|.|.||...||..
  Rat   518 RTIYQFQFQEALCQAAKHDG---------PLHKCDISNSTEAGQKLLNMLSLGNSGPWTLALENV 573

  Fly   759 LREGRLDGTALREYFAPLEEWLRQENLRTNEYVGWNYD-GDYCKRSIE 805
            :....:|...|..||.||..||:::|  .|..|||:.| ..|..:||:
  Rat   574 VGSRNMDVKPLLNYFQPLFVWLKEQN--RNSTVGWSTDWSPYADQSIK 619

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.