Protein Alignment Ance-3 and Ace3

DIOPT Version :10

• Sequence 1: NP_001033904.1
• Gene: Ance-3 / 34808
• FlyBaseID: FBgn0032536
• Length: 844
• Species: Drosophila melanogaster
• Sequence 2: XP_006533116.1
• Gene: Ace3 / 217246
• MGIID: 3644400
• Length: 774
• Species: Mus musculus
• Alignment Length: 685
• Identity: 255/685 - (37%)
• Similarity: 375/685 - (54%)
• Gaps: 49/685 - (7%)

  Fly   180 PFLSNQDRFNLNQGYLERQRYQQDRRYQQELEKLRILLVESDQKGSLECTANVAAQWNFETNVND 244
            |:|......:||..|.|.|              .::.|...:|...:.....:.|.||:.||:..
Mouse    37 PWLRTVGETSLNDFYSEAQ--------------AKLFLQFYEQTAQVVLNEFMEATWNYVTNITK 87

  Fly   245 FTQTEALNAQQRYVEFQRITAEQSKRINKDLIFDRRLYRQLMLQSEVGPNALP----LDVLD--- 302
            ..|...|..:....:|....:.:::....|...::.:.|.|.....:..:|||    |:|.|
Mouse    88 QNQKNMLQKEADRSQFMLYFSTRARMFRTDHFLNQDVKRMLRKLQNIDKSALPTEDLLEVTDRGP 152

  Fly   303 ------------RYNRLLNEMLFLYNSAEICAYQQPFQCDLHYIPQLKDIMAKSRDWDELQHTWV 355
                        ||||||..|...||.||:|..:.|  | |...|.|::|||.|||..||...|.
Mouse   153 GRPGTHTPAPERRYNRLLTYMETAYNRAEVCLDEGP--C-LTLEPDLQEIMATSRDQKELLWAWQ 214

  Fly   356 EYHRKAGRGMRDSYEQLIDVMQEVAYVNNVTNGGEYWYLAYESGNFRQDMDIVWEQIRPLYEGLH 420
            .:....||.:|..:|..:.:..:.|..|...:.|..|...|||....:|::.::::::|||..||
Mouse   215 GWRDAVGRQLRPVFEDYVRLSNKAAQYNGYKDMGALWRSKYESDTLEEDLEQLYKELQPLYLNLH 279

  Fly   421 AYVRRKLRDYYGPDRINRIAPIPSHILGNMYGQSWSNVLDILIPYPGRKLIDVTPRMVEQGYTPQ 485
            |||||.|..||||:.|:...|||:|:||||:.|||:|:||:::|||.:...|:|..|..|.:.|:
Mouse   280 AYVRRSLYRYYGPELIDLRGPIPAHLLGNMWAQSWNNILDLVLPYPTKAPEDITAIMKIQHWRPE 344

  Fly   486 LMFQLAEEFFTSINMSAVGPEFYRNSIFEQPLD-RRVLCEPSAWDFCNRHDFRVKICTDINQRSL 549
            .||:.|..||||:.|....|.|:..|:.|:|.| |.|.|..|:|:|...:|||||.||::....|
Mouse   345 KMFEEANLFFTSMGMLPAPPAFWIKSMMEKPADGREVECHTSSWNFYKFNDFRVKKCTEVTLEDL 409

  Fly   550 ISVHHEMAHIQYFLQYRHLPKIFRNGANPAFHQAVGDAIGLSVSTPRHLQTLGLLQRSLDESSYD 614
            :||.|:|.||||||||::|..|::.||:|||.:|||..|.||||:.::|...|||.:...:|..:
Mouse   410 LSVFHQMGHIQYFLQYQNLSVIYQEGASPAFEEAVGSVIALSVSSHKYLLARGLLSQPHQDSEEE 474

  Fly   615 INYLFTMAIDKVAFLPFALSLDNWRYDVFSGNANKRTMNCHYWNLREKYSGIKPPVLRSEKDFDP 679
            :|:|..:|::|:||:||:..:|.:|:.:|.|..:|.|.|..:||.|.||.|:.|||.||:.||||
Mouse   475 VNFLLGIALEKIAFIPFSYLVDKFRWKIFDGTISKITYNQEWWNFRLKYQGLCPPVPRSDDDFDP 539

  Fly   680 GAKYHIPANIPYIKYFFSTVLQFQIYRGLCRESGQYVPGDPRKPLHQCDIYRQPAAGNILKTLMS 744
            |||:|||||:|||:||...:||||::..||..||..      .||||||.|....||.||..|:.
Mouse   540 GAKFHIPANVPYIRYFLGLILQFQLHEALCEASGHV------GPLHQCDNYNSKVAGKILGDLLK 598

  Fly   745 KGASQPWQEVLEETLREGRLDGTALREYFAPLEEWLRQENLRTNEYVGWNYDGDYCKRSIETAGL 809
            .|:|:||:|||:|...|..:...|...||.||.:||..||::..:.:||   .|:.....|....
Mouse   599 LGSSRPWREVLQEVTGESNISTKAFLTYFKPLMDWLVTENVKQGDTLGW---PDFSCSFEEKITS 660

  Fly   810 QVFGGYYNGATGQKSAPFLYPLILLIYLYFSLRLL 844
            :|   .:.|...:....:|...:||...:|.|.|:
Mouse   661 KV---SFLGTDTEPEQAYLGQWVLLSMSFFMLVLI 692

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ance-3	NP_001033904.1	M2_ACE	216..784	CDD:341055	234/587 (40%)
Ace3	XP_006533116.1	Peptidase_M2	51..647	CDD:460196	239/618 (39%)