Protein Alignment Ance-3 and acn-1

DIOPT Version :10

• Sequence 1: NP_001033904.1
• Gene: Ance-3 / 34808
• FlyBaseID: FBgn0032536
• Length: 844
• Species: Drosophila melanogaster
• Sequence 2: NP_001024453.1
• Gene: acn-1 / 180780
• WormBaseID: WBGene00000039
• Length: 906
• Species: Caenorhabditis elegans
• Alignment Length: 741
• Identity: 190/741 - (25%)
• Similarity: 310/741 - (41%)
• Gaps: 93/741 - (12%)

  Fly    97 PTPRVNFSDSPFSGARFSN---HNYGPISSTTERNYGNDANLNGRYSDVPYSSQ-GERNFNPNDQ 157
            |.|..:.:..|....:|.|   .:||.::.|..                  |:| .|.|....:|
 Worm    81 PEPEPSPTPEPEPAIKFDNIESEDYGDVAETAA------------------STQPDELNTEVIEQ 127

  Fly   158 YNYNNNPNVEFVGINNRNR---FENPFLSNQDRFNLNQGYLERQRYQQDRRYQ-----QELEKLR 214
            . .:...|...:..|..|:   |.||         :.|..:....|.:....|     ::.||||
 Worm   128 L-VDTFLNTGSIASNKTNKGPVFANP---------VAQALVNSSNYWKTDNLQAPGSIKDEEKLR 182

  Fly   215 ILLVESDQKGSLECTANVA-AQWNFETNVNDFTQTEALNAQQRYVEFQRITAEQSKRINKDLIFD 278
            ..|...:.: :::....|| :.|.:..:.:...:.....|:.....|.|.|:.|:|:.:...:.|
 Worm   183 SWLAGYEAE-AIKVLREVALSGWRYFNDASPSLKLALDEAENVLTMFVRSTSMQAKQFDMASVTD 246

  Fly   279 RRLYRQLMLQSEVGPNALPLDVLDRYNRLLNEMLFLYNSAEICAYQQPFQCDLHYIPQLKDIMAK 343
            .::.|||...|..|.:||.......|::....:......:.||....|..|.|..| .:..|...
 Worm   247 EKVMRQLGYVSFEGMSALAPSRFADYSQAQAALNRDSKDSTICDKDVPPPCALQKI-DMDSIFRN 310

  Fly   344 SRDWDELQHTWVEYHRKAGRGMRDSYEQLIDVMQEVAYVNNVTNGGEYWYLAYESG--------N 400
            .:|...|||.||.|.....:. :.||..:|.:..|.|.:|...|||..|..|::..        :
 Worm   311 EKDASRLQHLWVSYVTAIAKS-KPSYNNIITISNEGAKLNGFANGGAMWRSAFDMSSKVHKAEFD 374

  Fly   401 FRQDMDIVWEQIRPLYEGLHAYVRRKLRDYY-GPDRINRIAPIPSHILGNMYGQSWSNVLDILIP 464
            ..:.:|.::..|:|.|:.||||:||:|...| .|..:::..|||:|:.|::.|..||...:...|
 Worm   375 LNKQIDKIYSTIQPFYQLLHAYMRRQLAGIYSNPVGLSKDGPIPAHLFGSLDGGDWSAHYEQTKP 439

  Fly   465 YPGRKLIDVTPRMV-----EQGYTPQLMFQLAEEFFTSINMSAVGPEFYRNSIFEQPLDRRVLCE 524
            :...   ..||..:     .|.||.:.||..|..:|.|.....:...::.:|||.:...:.::|.
 Worm   440 FEEE---SETPEAMLSAFNTQNYTTKKMFVTAYRYFKSAGFPHLPKSYWTSSIFARVWSKDMICH 501

  Fly   525 P-SAWDFCNRHDFRVKICTDINQRSLISVHHEMAHIQYFLQYRHLPKIFRNGANPAFHQAVGDAI 588
            | :|.|....:|||||.|..:.:......|..:....|...|:....:||..|:|....|:.:|.
 Worm   502 PAAALDMRAPNDFRVKACAQLGEPDFEQAHSLLVQTYYQYLYKDQSLLFREQASPVITDAIANAF 566

  Fly   589 GLSVSTPRHLQTLGLL-QRSLD-ESSYDINYLFTMAIDKVAFLPFALSLDNWRYDVFSGNANKRT 651
            ....:.|.:|.:..|: ...|| :.|..||.|:..:::....|||.::.|||||::|.|...|..
 Worm   567 AHLSTNPHYLYSQKLVPSEHLDIKDSVIINKLYKESLESFTKLPFTIAADNWRYELFDGTVPKNK 631

  Fly   652 MNCHYWNLREKYSGIKPPVLRSEKDFD-----PGAKYHIPANIPYIKYFFSTVLQFQIYRGLCRE 711
            :|..:|.:|.||.|::.|...:..:.|     ..::.|.||....|.|    ||:|||.:.||.|
 Worm   632 LNDRWWEIRNKYEGVRSPQPYNTSNLDALIHNSVSQVHSPATRTLISY----VLKFQILKALCPE 692

  Fly   712 -----SGQYVPGDPRKPLHQCDIYRQPAAGNILKTLMSKGASQPWQEVLEETLREGRLDGTALRE 771
                 .|..:..|..:.|.:               .|..|:|..|.:.||....:|.||...|.|
 Worm   693 GTILSEGCILSEDTTEKLRE---------------TMKLGSSITWLKALEMISGKGELDAQPLLE 742

  Fly   772 YFAPLEEWLRQENLRTNEYVGWNYDG 797
            |:.||..|||..|......|||:.:|
 Worm   743 YYEPLINWLRNTNEIDQVVVGWDGEG 768

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ance-3	NP_001033904.1	M2_ACE	216..784	CDD:341055	159/595 (27%)
acn-1	NP_001024453.1	Peptidase_M2	175..764	CDD:460196	165/613 (27%)
		EB	<794..824	CDD:460294